Background: The climate change and particulate matter emission contented of bioaerosols is known as an important reason of increasing the allergic interactions especially in patients with defect in immunity system. The aim of this study was to investigate fungal bioaerosol concentrations in relation to particulate matter (PM₁₀, PM_2.5 and PM₁) in indoor parts and ambient air of the generd educational hospital of Khorramabad city.

Materials and Methods: In this descriptive-analytical study, 192 samples (168 for indoor and 24 for outdoor) were gathered during 6 months at the seven indoor wards and one outdoor unit using Quick Take-30 method  at an airflow rate of 28.3 L/min and sampling time of 2.5 min on to Sabouraud dextrose agar medium containing chloramphenicol. The sampling of particulate matter was carried out by Monitor Dust-Trak 8520. Also, the relative humidity and temperature were surveyed by TES-1360 digital.

Results: The results showed that infectious ward with 101.7 CFU/m³ was as the most contaminated part and operating room with 46.4 CFU/m³ was the cleanest part. Cladosporium with 36.75% and Rodotorolla with 1.3% had higher and lower of fungi rates, respectively. The rate of  I/O<1  illustrate that this contamination had an outdoor source.

Conclusion: The surveys demonstrated that the increase of temperature and relative humidity have an effective influence on the pollutant accumulation. In addition, between fungi bioaerosols frequency and particulate matter ther was a significant correlation.