Background : Parkinson's disease (PD) is a progressive degenerative disorder with multiple motor and non motor symptoms. These features can cause disability and extensive dysfunction in patients. This study is conducted to evaluate the disabilities of PD patients. Materials and Methods: The study was case series. Depression, cognitive impairment and disability of patients were diagnosed based on DSM-IV criteria, Mini Mental State Examination and Hoen and Yahr criteria, respectively. Smelling dysfunction was diagnosed with water, rosewater, tobacco and coffee. Results: From 79 patients who were recruited in our study male to female ratio was 3 to 1. The most patients aged 70-79 years. Prevalence of depression and cognitive impairment was 45.6% and 68.4%. Prevalence of on-off phenomenon, falling attacks and olfactory dysfunction was 21.5, 32.9 and 68.4 percent, respectively. Duration of disease and treatment was significantly associated with amount of disability. Depression was significantly(p=0.006) associated with disability and severity of disease. Conclusion: This study showed that motor and non motor abnormalities are common in PD. Disability is influenced by factors such as age, duration of disease and treatment. Hence, diagnosis and treatment of PD should be considered before onset of disabilities.

Keywords: Parkinson\'s disease, Disability, Hospitalized patient, Clinic.

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