@article{ author = {Hedayatifar, Roshanak}, title = {Evaluation the rate of trans fatty acids isomers in ghee and tail sheep consumption in Lorestan}, abstract ={Background: Trans fatty acids are known as the most harmful type of dietary fats. Food and Drug Administration (FAD) has announced that TFAs consumption should be reduced to less than 1% of energy consumption. The aim of this study was to compare the amount of fatty acids with emphasis on trans fatty acids of ghee (animal oil) and tail sheep. Materials and Methods: 10 samples of ghee and 5 samples of tail sheep were transformed into methyl ester and analysis of fatty acid methyl esters were performed by gas chromatography (GC) with 100 meter capillary column and flame ionization detector (1m lit injected to GC). Results: Results show that total trans fatty acid in tail sheep samples were 4.3 ± 2.5 and total saturated fatty acid were 47.6 ± 4.7 g/100g fat,  and in ghee oil samples were 0.3 ± 0.1 and 40.7 ± 6.4 g/100g fat, respectively. Conclusion: Ghee and tail sheep contains high percentage of saturated fatty acids including trans and saturated fatty acids. Therefore, people who consume these foods may put themselves at elevated risk of cardiovascular disease.}, Keywords = {Trans fatty acids, Ghee, Tail sheep, Gas chromatography}, volume = {19}, Number = {2}, pages = {1-8}, publisher = {Lorestan University of Medical Sciences}, url = {http://yafte.lums.ac.ir/article-1-2538-en.html}, eprint = {http://yafte.lums.ac.ir/article-1-2538-en.pdf}, journal = {Yafteh}, issn = {1563-0773}, eissn = {2981-0779}, year = {2017} } @article{ author = {Nabiuni, Mohamad and Kouchesfahanii, Homa and Azari, Sakineh and Delfan, Bahram}, title = {CytotoxicEffect of Curcumin on Proliferation of HT_29 Cell Line}, abstract ={Background:Digestive system is the most common type of cancer in Iran with 38 percent of the cases.The risk of this cancer is influenced by both environmental and genetic factors. Curcumin is kind of phytochemicals which is important in chemoprevention strategy, in order to slow, block, or reverse the process of carcinogenesis.Researchhave shown that the possible role of curcumin to prevent or delay the diagnosis of colorectal cancer. In this research the effect of curcumin on proliferation of HT_29 cancerous cells were assayed. Materials and Methods:In this experimental research HT_29 cell line were cultured in DMEM medium containing 10% FBS (Fetal Bovine Serum, Gibco, Invitrogen) and 100 U/ml penicillin and 100mg/ml streptomycin. Different concentrations of curcumin on the growth of HT_29 cells were determined by MTT assay and the type of death induced was assessed by DAPI staining method.All experiments were done three times and data were analyzed byone –way ANOVA test and Instate 3 software. Results:The cell growth-inhibiting rate was about 53% at 50μM curcumin concentration after 24h of treatment(IC50). Vacuolation and significant decrease of cells were observed after 72h of treatment. Moreover, induction of apoptosis was observed with the DAPI staining method. Conclusion:According to molecular mechanisms of cell proliferation and curcumin ability in the induction of pro_apoptotic proteins and the inhibition of anti_apoptotic proteins as well as inhibition of as survival pathways,like NF_KB and AKT, this predisposition makes curcumin a good anticancer drug.}, Keywords = {Curcumin,Colon cancer,HT_29 cancer cell line, Proliferation}, volume = {19}, Number = {2}, pages = {9-17}, publisher = {Lorestan University of Medical Sciences}, url = {http://yafte.lums.ac.ir/article-1-2539-en.html}, eprint = {http://yafte.lums.ac.ir/article-1-2539-en.pdf}, journal = {Yafteh}, issn = {1563-0773}, eissn = {2981-0779}, year = {2017} } @article{ author = {Movahedi, Masomeh and EbadiRad, Mohamad and Kariminejad, kolsom and Moravej, Fayezeh}, title = {The effectiveness of Cognitive Behavioral and Behavior management Therapies on Procrastination in students of Lorestan University of Medical Sciences}, abstract ={Background: The researches of recent two decades are representative of the importance and special attention of various countries to the procrastination issue. This research carried out with the aim of the investigation of the effectiveness of cognitive behavioral and behavior management therapies on procrastination in students of the Lorestan University of Medical sciences. Materials and Methods: The experimental study method was used in this study that the design of pretest- posttest with experimental and control groups were used. Among the all of the male and female students in academic year of 2014, 393 subjects were selected as a sample of study using the convenient sampling method. At first the Tuckman' procrastination questionnaire were completed by 393 students and among them 76 subjects that diagnosed with procrastination were selected and assigned to experimental and control groups. Result: The findings of this research indicated that the amount of the prevalence of procrastination in all students was 19/33%. 29/41% of the male population under study had procrastination, but this amount for females were 14/96%. Also the results represented the effectiveness of two therapies of cognitive behavioral and behavior management on reduction of procrastination. Furthermore, there were significant differences between the gender and the type of the treatment. Conclusion: According to the results of this study, it seems that the procrastination is from the impressible cognitive constructs and regarding this issue, these two treatments by emphasis on cognitive constructs could decrease the amount of the procrastination on experimental groups.  Also the differences between the treatment methods among male and female, is representative of differences of cognitive constructs corresponding to the gender that seems not to be irrelevant to gender roles.}, Keywords = {Procrastination, Treatment, Cognitive behavioral, Behavior management, Students}, volume = {19}, Number = {2}, pages = {18-29}, publisher = {Lorestan University of Medical Sciences}, url = {http://yafte.lums.ac.ir/article-1-2541-en.html}, eprint = {http://yafte.lums.ac.ir/article-1-2541-en.pdf}, journal = {Yafteh}, issn = {1563-0773}, eissn = {2981-0779}, year = {2017} } @article{ author = {Hasanvandi, Saba and Ghazi, SHirin and Ghadampour, Ezato Lah}, title = {The effect of positive therapeutic program on psychological well-being of women with ADHD children}, abstract ={Background: The present study was to evaluate effectiveness of positive therapeutic program on psychological well-being in women with ADHD children. Materials and Methods:  This study was quasi-experimental and pretest-posttest with control group kind. The study sample consisted of 50 mothers in 2015-2016. Convenience sampling was applied to select the participants. Participants were quite randomly divided into two groups of 25 individuals. These groups were randomly divided into two groups of experimental and control groups. The experimental group received positive program and the control group received no intervention. The therapeutic packages of the positive were conducted for six sessions. Before and after the experiment all of the participants responded to the psychological well-being questionnaire. Three months after the experiment, i.e. the follow-up stage, in order to check storage of the program's effects, the participants answered the instrument. The data were analyzed by covariance (MANCOVA) test using SPSS 18.0. Results: The results of this study showed that positive program resulted significant effect in all of six components of psychological well-being. It should be noted that all of the results were significant at (p< 0.05) (DF 48, 2) and its effect maintain three months after the experiment (p< 0.05). Conclusion: Regarding to results, the positive therapeutic program can be effective in decreasing psychological problems. Also, this program is useful in promoting mental health among mothers with psychological problems such as ADHD. }, Keywords = {Positive psychology, Positive therapeutic program, Psychological well-being, Mothers, ADHD children}, volume = {19}, Number = {2}, pages = {30-40}, publisher = {Lorestan University of Medical Sciences}, url = {http://yafte.lums.ac.ir/article-1-2542-en.html}, eprint = {http://yafte.lums.ac.ir/article-1-2542-en.pdf}, journal = {Yafteh}, issn = {1563-0773}, eissn = {2981-0779}, year = {2017} } @article{ author = {Etemadfar, Lida and Shams, Nemat and Jaidari, Ami}, title = {Genomic Detection of Coxiella burnetii in Raw and Unpasteurized Cow Milk of Traditional domestic dairy products Vendors in Khorramabad, Lorestan Province in 2015}, abstract ={Background: Q fever is a widespread zoonotic disease that is caused by obligate intracellular bacteria, Coxiella burnetii. Raw milk or dairy products that are produced from unpasteurized milk may contain virulent Coxiella burnetii. The objective of this study was to determine the prevalence rate of C. burnetii in raw and unpasteurized cow bulk tank milk samples of traditional domestic dairy products vendors in Khorramabad, Iran. Materials and Methods: In this cross - sectional study a total of 120 raw and unpasteurized cow bulk tank milk samples in traditional domestic dairy products vendors were collected from October 2015 to November 2015 and tested for C. burnetii used a nested PCR assay. Results: In this survey, 9 out of 120 (7.5%) raw and unpasteurized cow bulk tank milk samples were found PCR positive for C. burnetii. Conclusion: The Results of this study indicate that raw and unpasteurized cow bulk tank milk samples in traditional domestic dairy products vendors are an important source of C. burnetii infection in Khorramabad.}, Keywords = {Nested PCR, Q - fever, Raw milk, Khorramabad}, volume = {19}, Number = {2}, pages = {41-49}, publisher = {Lorestan University of Medical Sciences}, url = {http://yafte.lums.ac.ir/article-1-2543-en.html}, eprint = {http://yafte.lums.ac.ir/article-1-2543-en.pdf}, journal = {Yafteh}, issn = {1563-0773}, eissn = {2981-0779}, year = {2017} } @article{ author = {Mirrezaee, Noshin and Dakhili, Mohamad and Mehrpour, SHahi}, title = {Effects of antifungal Rue on the candida albicans isolated from patients with vaginitis on in vitro during spring and winter seasons and comparison with two antibiotics}, abstract ={Background : Fungi  resistance to antifungal agents is one of the most common problems in medicine. Herbal remedies increased use in the traditional medicine an interesting and unexplored source of assessing new drug. Some plant essential oils, including Rue   (Rue officinalis L)  have anti– fungaleffects and they can be used as antimicrobial agents in treatment of infections. Hence, the aim of this study was to evaluate the compounds of essential oil and the anti – microbial properties of  its essential oil. Materials and Methods: In this experimental study, Ruta graveolens of Agriculture Research Center in Qom were collected . The essential oils were extracted, the inhibitory zone diameter and minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MIC, MFC), 140 candida isolates from patients referred to the clinic in women. Results: The mean inhibition in the disk diffusion method essential oils and ethanol extract  in the spring on the isolates, 19.71± 2.50 mm and 16.19 ± 1.9 mm  were respectively, and in the winter 21.16 ±3.7mm  and 18.32± 2.2 mm, respectively. Conclusion: The results of this study, Rue  essential oil and extract on candida albicans inhibitory effect .}, Keywords = {Rue, Candida, Vaginitis, Anti-fungal, Essential oils, Extracts}, volume = {19}, Number = {2}, pages = {50-59}, publisher = {Lorestan University of Medical Sciences}, url = {http://yafte.lums.ac.ir/article-1-2544-en.html}, eprint = {http://yafte.lums.ac.ir/article-1-2544-en.pdf}, journal = {Yafteh}, issn = {1563-0773}, eissn = {2981-0779}, year = {2017} } @article{ author = {Osali, Ali and Choobineh, Sirous and Soori, Rahman and Ravasi, Ali Aasghar and Mostafavi, Hosei}, title = {The Effect of Three-Month Aerobic Exercise with Moderate Intensity on IL1β, IL-6, and brain volume in 50-65 Years Old Women with Metabolic Syndrome}, abstract ={Background:  The increasing of age, inflammatory factors¸ and metabolic syndrome are the effective reasons in the reduction of  brain volume. The aim of this research was to investigate the effect of twelve week aerobic exercise with moderate intensity on IL1β, IL-6, and brain volume in 50-65 years old women with metabolic  syndrome. Materials and Methods: 24 women with Metabolic Syndrome (MetS) took a part voluntarily. They were divided into two groups, MetS exercise (EM), MetS control (CM). ME group participated in an aerobic exercise training (AT) program (for 12 weeks), three sessions per week, each session contained three performing parts and two relaxing parts, at the beginning, each part contained eight minutes. Also each week, one minute added to performing sets. MRI and blood samples were conducted before and after three month to evaluate the levels of IL1β, IL-6, and brain volume. Data were analyzed by paired-sample of T-Test, and independent samples of T-Test. Results: Brain volume afterthree  month doesn't significantly changed, but IL1β, and IL-6 after tree month exercise were significantly decreased (P<0.05). Also, there were not significantly different in brain volume, IL1β, and IL-6 pre and post test in the control group. Conclusion: These findings indicate that three months aerobic exercise with a moderate intensity ameliorate inflammatory factor and doesn't change brain volume. Maybe with adjusting, the time and intensity of exercise brain volume will be increased.}, Keywords = {Aerobic exercise, IL1β, IL-6, Brain volume, Metabolic syndrome}, volume = {19}, Number = {2}, pages = {60-71}, publisher = {Lorestan University of Medical Sciences}, url = {http://yafte.lums.ac.ir/article-1-2545-en.html}, eprint = {http://yafte.lums.ac.ir/article-1-2545-en.pdf}, journal = {Yafteh}, issn = {1563-0773}, eissn = {2981-0779}, year = {2017} } @article{ author = {Kohneshin, Behzad and Piree, Maghsod and Matinhomaee, Has}, title = {Evaluation and comparison of endurance training with fluoxetine 4 weeks on depression and heart 1β adrenergic receptors in male Wistar rats}, abstract ={Background : Long-term exposure to anxiety and depression puts myocardium at risk of failure. Neurohormone Message caused be depression delivered to the heart by beta1 adrenoreceptor. The aim of this study was to survey and compare the effect of 4 weeks of endurance training with fluoxetine treatment on beta-adrenergic receptors in the male Wistar rat heart. Materials and Methods: This research method is experimental. In this study, 24 male Wistar rats divided randomly into three groups. To each of the rats, exercise and supplementation group, fluoxetine 0.8 mg /kg of body weight LPS injected Intraperitoneal. Exercise group run for the 4-week on the treadmill at a speed of 20 meters per minute for 45 minutes each day. Fluoxetine group received 0.5 mg of oral fluoxetine. To prove the effects of LPS injection per and post FST test results analyzed using T-test for dependent samples. Pre and post-test FST data for each group using T-test at a significance level( α <0.05), and cardiac receiver data were analyzed by one-way ANOVA.   Results: The mean density of beta-1 adrenergic receptors in the training group were significantly lower than the depressed group (P <0.05). The mean density of beta-1 adrenergic receptors in the training group were  not significant in comparison to the fluoxetine group. Conclusion: Endurance training can prevent a significant increase in the density of adrenergic beta-1 receptors in the heart of the depressed rats.  }, Keywords = {Intense Endurance Exercise, Beta-1 Adrenergic Receptor, FST Test}, volume = {19}, Number = {2}, pages = {72-81}, publisher = {Lorestan University of Medical Sciences}, url = {http://yafte.lums.ac.ir/article-1-2546-en.html}, eprint = {http://yafte.lums.ac.ir/article-1-2546-en.pdf}, journal = {Yafteh}, issn = {1563-0773}, eissn = {2981-0779}, year = {2017} } @article{ author = {Moradi, Behzad and Teymouri, Hasan and Porya, Ali and Khademi, Mozhgan and Ebrahimzadeh, Farz}, title = {The effect of two different levels of positive end expiratory pressure (PEEP) in the incidence of atelectasis after coronary artery bypass graft surgery}, abstract ={Background: The incidence of atelectasis after coronary artery bypass graft surgery is highly recommended due to the impact of different levels of PEEP to prevent these complications. The aim of this study was to investigate the effects of different levels of PEEP after coronary artery bypass graft surgery. Materials and Methods: This study was performed by clinical trial. The sample size in this study was 90 patients. Non-probability sampling was conducted in consecutive patients that using a stratified block randomized to intervention and control groups (each group n = 45). In the control group of patients after surgery, upon arrival in the intensive care unit until tracheal extubation rates PEEP of 5 cm H2O received Patients in the intervention group after entering the intensive care unit for 4 hours average PEEP of 10 cm H2O received. Six hours after tracheal extubation atelectasis of the final diagnosis of chest radiographs, oxygen saturation and body temperature were used. For statistical analysis, chi-square test and t-test used. Results: The incidence of atelectasis in the intervention group, in 7 patients were about (15.6%) in the control group, and in 16 patients were about (35.6%) which was statistically significant difference (P= 0.03). The mean arterial oxygen saturation was more higher in the intervention group rather than the control group and the difference was statistically significant (P= 0.025). Conclusion: This study shows that the use of PEEP levels of 10 cm H2O after coronary artery bypass graft surgery can reduce the incidence of postoperative atelectasis. So, it is recommended to use this method in order to reduce the incidence of atelectasis.}, Keywords = {Positive end expiratory pressure (PEEP), Coronary artery bypass graft surgery (CABG), Atelectasis}, volume = {19}, Number = {2}, pages = {82-92}, publisher = {Lorestan University of Medical Sciences}, url = {http://yafte.lums.ac.ir/article-1-2547-en.html}, eprint = {http://yafte.lums.ac.ir/article-1-2547-en.pdf}, journal = {Yafteh}, issn = {1563-0773}, eissn = {2981-0779}, year = {2017} } @article{ author = {Dadgar, Reza and Jahani, Mohamad and Mahmoudi, GHahrem}, title = {The impact of health system reform plan on the hospital\'s performance indicators of Lorestan University of Medical Sciences}, abstract ={Background : Health systems in order to confirmity with changing conditions and responding to community needs, community needs to change and continuous improvement of their structure,  function, and subsequent evaluationindicators. Therefore the purpose of this study was to evaluate effect of health system reform plan on performance indicators. Materials and Methods : This study was a cross-sectional descriptive study using data from the years 1392 to 1394, the years before and after the implementation of healthcare reform was carried out. The population consisted of all hospitals of the Lorestan University of Medical Sciences (14 Hospitals). For data analysis using SPSS version 16, Paired sample T tests and Wilcoxon software were used. Results: After health system reform plan all indicators had better than before and this development  was significant in all cases. After health reform plan average length of stay was slightly increased (0.5%), although this was not significant statistically (P = 0.653). Before the health reform plan, the difference between the average bed occupancy indicator only for educational and non-educational centers were significant statistically (p = 0/05), but after the reform mean for all the indicators except indicator of average length of stay (p = 0/038), was significant. Conclusion: The health system  reform plan has been positive changes in indicators of hospital performance. Therefore, while considering the current trend of continuous improvement, the continuity of the project was advised based on the results of this study.}, Keywords = { Healthcare reform, Performance indicators, Evaluation, Hospitals, Lorestan}, volume = {19}, Number = {2}, pages = {93-102}, publisher = {Lorestan University of Medical Sciences}, url = {http://yafte.lums.ac.ir/article-1-2549-en.html}, eprint = {http://yafte.lums.ac.ir/article-1-2549-en.pdf}, journal = {Yafteh}, issn = {1563-0773}, eissn = {2981-0779}, year = {2017} } @article{ author = {Tavalaee, Raedeh and Moazedi, Ahmad Ali and Gharibnaseri, Mohamad Kazem and Akhond, Mohamad Rez}, title = {The role of muscarinic receptors in contractions of adult male Rat\'s isolated ileum}, abstract ={Background: The effects of cholinergic system are applied through both nicotine and muscarinic receptors. Considering to muscarinic receptorsexistence in therat ileum, in this researchthe effectof carbachol (muscarinic receptor agonist) and scopolamine (muscarinic receptor antagonists) on the ileum contraction induced by KCl in adult male rats were studied. Materials and Methods: The distal part of Wistar rat’s ileum was separated and its contractions were recorded under one gr stretching and 37 degree temperature in the bathroom containing the solution of Tyrode by Isotonic method. The ileum tissue separately affected by KCl then carbachol in the first group, KCl then scopolamine in the second group, scopolamine for 30 minutes then KCl in the third group and 10-3 M concentration of scopolamine for 30 minutesthen 10-2 M concentration carbachol in the fourth group. Results: There was a significant difference between zero concentration and (10-2,10-3,10-4mg/ml) concentrations of carbachol (P<0.001). There was a significant difference between zero concentration and 10-3 M concentration of scopolamine (P<0.01) and also the values of 10-4, 10-6M (P<0.001). There was a significant difference between zero concentration and 10-3 M concentration of scopolamine (P<0.01) and also the values of 10-4M (P<0.001) and 10-6M (P<0.05) when scopolamine was exposed tissue for 30 minutes. Conclusion: This study showed that different concentrations of carbachol enhance induced contraction by potassium chloride in a concentration-dependent manner and has a synergistic effect with potassium chloride. Also, different concentrations of scopolamine decrease induced contraction by potassium chloride in a concentration-dependent manner.}, Keywords = {Contraction, Ileum, Carbachol, Scopolamine, Rat}, volume = {19}, Number = {2}, pages = {103-114}, publisher = {Lorestan University of Medical Sciences}, url = {http://yafte.lums.ac.ir/article-1-2550-en.html}, eprint = {http://yafte.lums.ac.ir/article-1-2550-en.pdf}, journal = {Yafteh}, issn = {1563-0773}, eissn = {2981-0779}, year = {2017} } @article{ author = {Afrouzan, Hoshang and AbouieMehrizi, Akram and Shokrgozar, Mohamad Ali and Tahghighi, Azar and Eshaghi, Ali and DinparastDgadid, Navid and Zakeri, Sedigheh}, title = {Assessment of the cytotoxicity and in vivo anti-Plasmodial activity of ethanol and dichloromethane extracts of four different Iraninan propolis}, abstract ={Background: The emergence of antimalarial drug resistance is one of the great problems of malaria control and elimination of worldwide. In order to overcome anti-malarial drug resistance, cytotoxicity and in vivo anti-Plasmodiumal activity of four different Iranian propolis were investigated. Materials and Methods: Four Iranian propolis samples were collected from four different regions of Iran and extracted by %70 ethanol and dichloromethane. The cytotoxicity of ethanolic and dichloromethane extract of propolis, using L969 fibroblast cell lines, were evaluated by MTT assay. The in vitro anti-Plasmodial activities of the propolis samples on BALB/c mice were assayed. Results:The cytotoxicity results showed that ethanol and dichloromethane extracts of four Iranian propolis samples at doses of 25, 50, 100 and 200 µg/ml were non-toxic (P<0.05). The highest percentage of growth inhibition against Plasmodium berghei with %71 and %65 was for ethanol and dichloromethane extract of Morad Byge propolis, respectively. Conclusion: Considering the drug resistance of P. falciparum to conventional medicine and its dangers, and the emergence of development cheap and safe anti-malaria drugs to control and eliminate programs. Further investigation on Iranian propolis as safe and anti-malarial drug is recommended.}, Keywords = {Iran, Propolis, Cytotoxicity, Anti-plasmodium}, volume = {19}, Number = {2}, pages = {115-125}, publisher = {Lorestan University of Medical Sciences}, url = {http://yafte.lums.ac.ir/article-1-2551-en.html}, eprint = {http://yafte.lums.ac.ir/article-1-2551-en.pdf}, journal = {Yafteh}, issn = {1563-0773}, eissn = {2981-0779}, year = {2017} } @article{ author = {Jafarzadeh, Mehezad and Mousavizadeh, Kazem and Joghataie, Mohamad Taghy and Asghari, Mohse}, title = {Effect of Fibroblast Growth Factor Antagonist Peptide on mouse Breast Tumor Growth and Serum Levels of Interleukin-8 and Tumor Necrosis Factor-Alpha}, abstract ={Background: Today, breast cancer is the biggest health threat to women. The current common treatments include surgery, chemotherapy, and radiotherapy. In most cancers, metastasis is the primary cause of treatment failure. Surgery and radiotherapy are effective on local tumors, but they cannot affect metastatic cancers. Chemotherapy is often used to treat metastatic cancers, the effectiveness of which is basically limited due to its toxic side effects at high doses. Due to the side effects of chemotherapy drugs, peptide therapy has become increasingly popular in the world. Accordingly, this study aims to investigate the effect of a designed bFGF antagonist peptide on inhibition of tumor growth in 4T1 metastatic breast cancer model and the serum levels of interleukin-8 and tumor necrosis factor-alpha. Materials and Methods: Female Balb/c mice (5-7 weeks old) were used in this study. Tumors were established using 4T1 tumor transplantation method. Treatment began after two weeks, when tumors reached an appropriate size. After that, the designed peptides at three selected doses were injected intraperitoneally for 14 days. Positive and negative controls were also used for each injection. The mice in the positive and negative control groups were injected with PBS and doxorubicin, respectively. Tumors size was measured every other day using a digital caliper, and their volume was measured using the formula: length × width2 × 0.5. After blood samples were taken from the mice’s eyes and plasma isolation was performed, interleukin-8 (IL-8) and tumor necrosis factor-alpha were measured by ELISA. Results: The data were analyzed by one-way analysis of variance (ANOVA) using SPSS. Given the value of p≤0.05, it can be concluded that peptide injection is effective in the reduction or inhibition of tumor growth. Significant differences are observed among the negative control group  positive contro, group, and the peptide-treated group. Conclusion: The results of this study showed that the anti-angiogenic peptide effectively inhibited the growth of the breast cancer and  the results indicate that compared with the negative control group, serum levels of interleukin-8 and tumor necrosis factor-alpha are significantly different.}, Keywords = {Peptide, Breast Cancer, Tumor Size, Interleukin-8, Tumor Necrosis Factor-Alpha}, volume = {19}, Number = {2}, pages = {126-135}, publisher = {Lorestan University of Medical Sciences}, url = {http://yafte.lums.ac.ir/article-1-2556-en.html}, eprint = {http://yafte.lums.ac.ir/article-1-2556-en.pdf}, journal = {Yafteh}, issn = {1563-0773}, eissn = {2981-0779}, year = {2017} }