2024-03-29T14:12:47+03:30
http://yafte.lums.ac.ir/browse.php?mag_id=23&slc_lang=en&sid=1
23-555
2024-03-29
10.1002
Yafteh
yafte
1563-0773
2981-0779
10.18869/acadpub.yafte
2011
13
3
The effect of daily therapeutic community model on personality traits of the substance abusers referred to Khorramabad TC center
Hedayat
Nazari
mailto:Nazari_hedayat@yahoo.com
Mandana
Saki
Masoume
Zareai Dehno
Mehdi
Birjandi
Background : Drug abuse and addiction is a social and medical burden which has drastic
consequences in the community. There has been various rehabilitative and healing programs
for the addicts.The conducted studies have shown that therapeutic community treatment
model is an appropriate method for restoring the addicts to society. The present study tries
to evaluate the impact of TC treatment programs on the addicts’ personality characteristics.
Materials and Methods: This interventional study includes all the male addicts for whom
the detoxification period has been finished. The subjects were selected using easy random
sampling method form clients referred to TC center. At the beginning of the study , SCL90
questionnaire was filled out by psychologist for each sample, then 60 cases were selected
based on the sample size formula. The subjects participated in a training TC program for
three months daily except weekends. At the end of a three-month program, SCL 90 was
given to the subjects to be completed and the data were gathered and analyzed.
Results: The results showed that the subjects before entering the study were: 16.7% normal
,40% border personality disorder ,30% sick and 13.4% very sick. After intervention of TC
,25% normal ,66.7% with suspicious,8.3% sick. None of the cases were highly sick after
the TC intervention.The mean of the marks for personality disorders before the TC
intervention was 2.4± 0.92,after the intervention it was 1.83 ± 0.56.The Willcoxson rating
test showed a significant difference between the severity of personality disorders before and
after the TC intervention(p<0.001).
Conclusion: As it was mentioned in the findings, the implementation of TC intervention
had a significant effect on the scores obtained for personality disorder. So administrators
and policy makers who are responsible for addiction control are recommended to develop
and support the centers for Therapeutic Community and endeavour to provide a life without
narcotic substances.
2011
12
01
1
8
http://yafte.lums.ac.ir/article-1-555-en.pdf
23-556
2024-03-29
10.1002
Yafteh
yafte
1563-0773
2981-0779
10.18869/acadpub.yafte
2011
13
3
Detection of N-RAS gene mutations in codons 12,13 and 61 in patients with pediatric acute lymphoblastic leukemia
Mahin
Behzadifard
mahin_behzadi@yahoo.com
Yosof
Mortazavi
Sadegh
Rezapour
Ali akbar
Pourfatholah
Saeed
Kavyani
Mansoure
Haghighi
Samane
Behzadifard
Background: Acute leukemia is the prevalent malignancy in pediatrics. One of the most important
causing factors of acute lymphoblastic leukemia is mutations of proto oncogenes and their chang in to
oncogenes. Activation of N-RAS proto-oncogene due to point mutations plays a major role in ALL
malignancy. Since there was no report on the frequency of N-RAS gene mutation in Iranian pediatric ALL
patients, therefore we decided to determine its frequency and compare the results with age, sex and type of
ALL.
Materials and Methods: In this study, 60 pediatric ALL patients from Tehran Mahak hospital were
screened for the mutations of N-RAS gene at codons 12 ,13 1nd 61.DNA was extracted from peripheral
blood samples before the start of chemotherapy. The above mentioned codons were amplified by PCR
and analyzed by restriction endonuclease enzymes.
Results: We could detect mutations in 7 cases of 60(11.7%) patients. Most of the mutations were detected
in males with an age less than 5 years old. The frequency of mutations for codons 12, 13 and 61 were
8.3%,3.3% and 1.7% respectively. Most of the mutations (71.4%) were found in c-ALL subtype.
Conclusion: We detected mutations in 11.7% of our ALL patients. In general , frequency of the
mutations that we found was in agreement with the results of other studies. However , to do study with
more patients and wider range of age using a combination of PCR-RFLP and direct gene sequencing is
highly recommended.
All
N-RAS gene
PCR-RELP
Proto-oncogene .
2011
12
01
9
15
http://yafte.lums.ac.ir/article-1-556-en.pdf
23-557
2024-03-29
10.1002
Yafteh
yafte
1563-0773
2981-0779
10.18869/acadpub.yafte
2011
13
3
Survey of Hydroxyproline in sausages produced by manufactures of Khorramabad
Ebrahim
Falahi
e_falahi@yahoo.com
Nahid
Ghazi
Background : Heated meat products such as sausage are one of the most adherents in Iran. So it needs
to be controlled and detected its fault for food security. The aim of the study was to determine the
amount of Hydroxyproline in sausages produced by manufactures located in khorramabad.
Materials and Methods: This cross sectional study was carried out on 30 samples of sausages
produced by Golbahar manufacture in Khorramabad city, 2009 summer.
Samples were collected from one production line based on sampling principals, and were transferred to
laboratory on proper condition. Amount of Hydroxyproline was measured by spectrophotometery
method. Collagen and collagen nitrogen were calculated by formula. Data were entered to SPSS
software and were analyzed by one way t test.
Results: Mean and standard deviation of Hydroxyproline was 0.017 and 0.009 g/ 100, respectively.
This amount was less than standard amount in Iran. Collagen and collagen nitrogen were 0.13±0.07 and
0.02±0.01 g/100, respectively.
Conclusion: In conclusion, the amount of Hydroxyproline, collagen and collagen nitrogen of sausages
produced by Golbahar manufacture were less than Iranian standard amounts. So fault probability in this
product may be low.
Hydroxyproline
Sausage
Food fault
Collagen
Khorramabad
2011
12
01
16
21
http://yafte.lums.ac.ir/article-1-557-en.pdf
23-559
2024-03-29
10.1002
Yafteh
yafte
1563-0773
2981-0779
10.18869/acadpub.yafte
2011
13
3
The effect of progressive muscle relaxation techniques on anxiety in Patients with myocardial infarction
Mozhgan
Jariani
Mandana
Saki
Mandana_saki@yahoo.com
Nahid
Momeni
Farzad
Ebrahimzade
Ali
Seydian
Background : Coronary and artery diseases are amongst the most common existed diseases in human societies. Thus considering too much stress that is created after myocardial infarction and the effect which anxiety can have on the treatment process of
myocardial infraction patients, This research was carried out to study the effect of applying progressive muscle relaxation of these patients.
Materials and Methods: This clinical trail study was done on sixteen patients with myocardial infarction afflicted to the disease two weeks before the beginning of the research.After selecting qualified samples , the patients were divided into two groups of intervention and control. Both groups were matched from view points of age, sex, and the amount of anxiety. In the first day, for each group the cattle anxiety questionnaire was completed and their vital signs were recorded, and then for the intervention group the progressive muscle relaxation technique was done during 3 sequential days and on the whole in 6 sessions. And again after 3days variables were measured. The gathered data were analyzed by SPSS software.
Results: In the intervention group anxiety, systolic and diastolic blood pressure had a significant decrease comparing to the control group (P<0.001),while decrease was not significant in the control group.
Conclusion: progressive muscle relaxation can reduce the amount of anxiety, and systolic and diastolic blood pressure of the patients with myocardial infarction hospitalized in CCU ward, therefore it can play an effective role as a supplement non-medicinal, simple and cheap treatment for these patients
Anxiety
Myocardial infarction
Progressive muscle relaxation.
2011
12
01
22
30
http://yafte.lums.ac.ir/article-1-559-en.pdf
23-560
2024-03-29
10.1002
Yafteh
yafte
1563-0773
2981-0779
10.18869/acadpub.yafte
2011
13
3
The effects of verjuice consumption on risk factors of profile lipid and development of atherosclerosis in hypercholesterolemic rabbits
Mahbobe
Setorki
Sedighe
Asgary
sasghary@yahoo.com
Monire
DoDi
Background : Nowadays, the role of anitioxidants in improvement and development of atherosclerosis has been demonstrated. In this study, we have investigated the effects of verjuice intake on risk factors of profile lipid and development of atherosclerosis in hypercholesterolemic rabbits.
Materials and Methods: Thirty two male New Zealand rabbits were randomly divided into four groups: normal diet group, a diet containing 1 % cholesterol, a diet containing 1 % cholesterol with 5ml verjuice, and a diet containing 1 % cholesterol with 10ml verjuice .The glucose, total cholesterol (TC), triglyceride (TG), apolipoprotein A(ApoA),apolipoprotein B(ApoB), serum glutamic pyruvic transaminase (SGPT), serum glutamic oxaloacetate transaminase (SGOT), HDL-cholesterol (HDL-C and antioxidative capacity were measured before the experiment and by the end period(2months). At the end of the study, fatty streak formation in aorta artery was determined in all groups.
Results: Using verjuice daily (5 and 10 ml) caused significant increase in antioxidative capacity and HDL-C in comparison with hypercholesterolemic diet. Both doses of verjuice significantly decrease in hepatic of transaminase (SGPT, SGOT), glucose and ApoB. Using 10 ml verjuice caused significant reduce TG in comparison with hypercholesterolemic diet.No significant difference was found between verjuice taking groups and hypercholesterolemic diet group in TC and ApoA. Histological results showed that administration of verjuice significantly lowered atherosclerotic lesion in aorta artery in comparison with hypercholesterolemic diet.
Conclusion: The results of this study suggest that there might be a protective effect of verjuice consumption on some of the risk factors of atherosclerosis particularly as an antioxidant.
Hyperlipidemi
Triglyceride
Antioxidant
2011
12
01
31
40
http://yafte.lums.ac.ir/article-1-560-en.pdf
23-561
2024-03-29
10.1002
Yafteh
yafte
1563-0773
2981-0779
10.18869/acadpub.yafte
2011
13
3
The effect of oral zinc sulfate on the growth of preterm infants
Shokofe
Ahmadipour
shokofe57@yahoo.com
Mitra
Hemmati
Homa
Babaei
Key ghobad
Ghadiri
Background : Zinc is a micro element which plays an important role in the growth of children. Neonates receive the major part of zinc during the third trimester of pregnancy, so preterm infants don’t have enough zinc storage.The aim of this study was to determine the effect of oral zinc sulfate on growth of preterm infants.
Materials and Methods: This study was carried out on 106 preterm neonates in the 28-36 weeks of gestational age bracket and between 1000-2500 gr in weight born in Imam Reza and Motazedi hospitals in Kermanshah city. They were randomly divided into two groups. Group 1 received 3 mg/day zinc sulfate for 6 months, but the second group did not received zinc. Both groups were visited monthly and measured for weight, length and head circumference.
Results: The mean age of group 1 and control group was (32.9±2.2 week) and (32.7±2.1 week) and at the end of month 6, mean weight in them was (6861.3± 810.3 gr) and (5118.9±534.7 gr) (P< 0.001) respectively. Significant difference in length and head circumference was not found until end of the second month but from third month, they were significant. The mean of length in zinc group was (59.8±3.8 cm) and in control group was (57.0±3.5cm) (P< 0.001) and the mean of head circumference was (41.4±2.0cm) and (39.5±2.5cm) (P< 0.001).
Conclusion:Zinc supplementation 3mg daily, for preterm infants for 6 months have significant effect on growth of neonates, weight, length and head circumference.
Infant
Preterm
Zinc sulfate
Growth
2011
12
01
41
45
http://yafte.lums.ac.ir/article-1-561-en.pdf
23-562
2024-03-29
10.1002
Yafteh
yafte
1563-0773
2981-0779
10.18869/acadpub.yafte
2011
13
3
Knowledge of health care providers about legal aspects of medical records in teaching hospitals affiliated to Lorestan university of medical sciences
Mohammad sadegh
Ahmadi
Abbas
Sheikhtaheri
A_shtaheri@razi.tums.ac.ir
Khalil
Kimiafar
Mojtaba
Esmaeili
Mahnaz
Mosavi
Background : Knowledge of healthcare providers, about ethical and legal aspects of healthcare, prepares providing conditions of patients, right. The aim ofthisstudy is to determine the knowledge of healthcare providers about legal aspects of medical records in teaching hospitals affiliated to Lorestan university of medical sciences in 2010.
Materials and Methods: In this cross-sectional study, 210 healthcare providers, selected randomly, including physicians, nurses and medical record personnel were surveyed and data gathered by a valid questionnaire designed based on regulations related to health information, related experts and reference texts. Data were analyzed through the mean score(± SD)of correct responses and SPSS software.
Results: The knowledge level of healthcare providers was moderate about legal aspect of confidentiality (3.79 ± 1.13 from 9 points), informed consent (4.47 ± 1.62 from 10 points) and issuing certificates (3.40 ± 1.52 from 11 points). Totally, the knowledge level was moderate (11.72± 4.53 from 30 points). Physicians had more knowledge and nurses less.
Conclusion: Educating legal aspects related to medical records including confidentiality, informed consent, and especially issuing certificates for all of healthcare providers specially nurses seems necessary.
Knowledge
Legal aspects
Confidentiality
Informed consent
Medical certificates.
2011
12
01
45
55
http://yafte.lums.ac.ir/article-1-562-en.pdf
23-563
2024-03-29
10.1002
Yafteh
yafte
1563-0773
2981-0779
10.18869/acadpub.yafte
2011
13
3
The relationship between obesity and serum total cholesterol, LDL cholesterol, HDL cholesterol and triglyceride level in men 18-34 years old living in district 6 of Tehran: comparison of BMI,waist and waist to hip ratio
Masoud
Kimiagar
sm_kimiagar @yahoo.com
Golbon
Sohrab
Mahvash
Hemat
Banafshe
Golestan
Background : Cardiovascular diseases are among the most important causes of mortality and major health problems in developed as well as developing countries including Iran. This study aimed to develop percentile reference data for serum lipids including total cholesterol, low density lipoprotein cholesterol, high density lipoprotein cholesterol and triglyceride and to determine the prevalence of overweight and fat distribution in male adults living in Tehran.
Materials and Methods: The study population consisted of 141 men aged 18-34 years living in district 6 of Tehran.According to list of primary schools located in district 6 of Tehran, subjects were chosen from residents around these schools. Sociodemographic and anthropometric questionnaires were filled in at the subjects' home. They were asked to attend the study center the next day at 8:00-8:30 am and 5 ml of fasting blood (at least 12 hours) was collected from each subject. Data statistical analysis was performed using SPSS software Ver 11.5. Chi square test was used for qualitative variables and Pearson correlation was calculated for quantitative variables.
Results: Data showed 24.8% hypercholesterolemia, 29.8% hypertriglyceridemia, 21.3% LDL>130mg/dl and 36.2% HDL<40mg/dl in the subjects. BMI was positively and significantly correlated with total cholesterol, triglyceride and low density lipoprotein cholesterol but no significant correlation was observed for waist circumference and waist to hip ratio with blood indices.
Conclusion: The study shows that BMI can be a predictive factor for cardiovascular disease in Iranian population. In order to clarify waist circumference and waist to hip ratio correlations with and blood lipids and also to develop percentile reference data for blood lipids, more studies with larger study population is recommended.
Blood lipids
Overweight
Obesity
Fat distribution
2011
12
01
56
63
http://yafte.lums.ac.ir/article-1-563-en.pdf
23-564
2024-03-29
10.1002
Yafteh
yafte
1563-0773
2981-0779
10.18869/acadpub.yafte
2011
13
3
Protective effect of hydroalcohlic olive leaf extract on inhibition of Gentamicin-induced nephrotoxicity in rat
Poran
Toolabi
pooran.toolabi @yahoo.com
Majid
Tavafi
Soheila
Ebrahimi
Sima
Nasri
Hasan
Ahmadvand
Background : Administration of Gentamicin is restricted due to its nephrotoxicity. Many studies have demonstrated that free radicals induced Gentamicin- nephrotoxicity. Olive leaf contains some antioxidant biophenols such as Oleuropin. In this study for the first time the effect of hydroalcohlic olive leaf extract on Gentamicin-induced nephrotoxicity was investigated.
Materials and Methods: 35 male Sprague-Dowley rates were randomly divided into five groups. The first group served as a control and injected with the normal saline. Nephrotoxicity induced by Gentamicin (100 mg/kg) in experimental groups for 12 days. Three groups were treated with hydroalcohlic olive leaf extract (25, 50 and 100 mg/kg respectively). The rats were killed on the twelfth day.Plasma Malondialdehyde (MDA) and creatinine concentrations were measured. Kidney sections were prepared and stained with PAS method for histopathological studies.
Results: hydroalcohlic olive leaf extract at 25, 50 and 100 mg/kg/d significantly reduced gentamicin-induced tubular necrosis (p<0.05) and inhibited decreases of proximal tubule volume density (p<0.05). hydroalcohlic olive leaf extract at 50 and 100 mg/kg/d significantly reduced lymphocyte infiltration in comparison with Gentamicin administrated rats (p<0.05). Gentamicin increased level of MDA. Treatment with extract (100 mg/kg/d), significantly reduced level of MDA compared with other groups (p<0.05).Use of extract at 25, 50 and 100 mg/kg/d significantly inhibited increase of serum creatinine (p<0.001). Treatment with extract (50 mg/kg/d), significantly inhibited increase of serum urea (p<0.05).
Conclusion: Hydroaleohlic olive leaf extract can reduce Gentamicin-induced nephrotoxicity and this effect is probably depends on antioxidant properties of this extract.
Olive leaf
Gentamicin
Nephrotoxicity
Antioxidant
2011
12
01
64
74
http://yafte.lums.ac.ir/article-1-564-en.pdf
23-565
2024-03-29
10.1002
Yafteh
yafte
1563-0773
2981-0779
10.18869/acadpub.yafte
2011
13
3
Impact determination of strength and resistance training on Glycoside hemoglobin and blood sugar on patients with type II diabetes”
Bahman
Hasanvand
Kobra
Karami
kbkarami@gmail.com
Abdollah
Khodadi
Mehdi
Valipour
Background : This study determined the impact of strength and resistance training on hemoglobin Glycoside and glucose in type II diabetic patients in Khorramabad in 2009.
Materials and Methods: This quasi-experimental study was carried out on 30 men with type 2 diabetes referred to laboratories in Khorramabad, selected by screening and interview and purposeful sampling . After the subjects completed questionnaires of medical records and written consent, they were randomly divided into three groups: endurance training, strength and control groups. Conditions for participants were: over 30 years of age, blood sugar 150-250, the absence of any other chronic disease and history of sports last three months, stroke, hypertension, diabetes and severe complications . Before training, the subjects were fasting for 8-12 hours and then blood sampling was performed. Strength training and endurance for 8 weeks under coach concerned were applied. Strength training includes 10 motions for muscles and for each move three to four sets and sets of 10 to 12 repeats were considered and the principle of overload followed during the eight weeks . Endurance exercise was running on a treadmill machine with a maximum heart rate 60%. Ten subjects in the control group followed and performed the recommendations till end of the study. After the eight-week training period, post test (blood test) done. Data were analyzed using SPSS statistical software.T pairs was used to compare means(Pre test, Post test).
Results: 29 subjects in three groups of exercises were conducted until the end. Average age, weight, BMI and the amount of drug in the three groups showed no significant difference statistically (p=0/76). Reduction in glaciated hemoglobin before and after the endurance test, showed significant differences (p =0/02 ).
Conclusion: This study shows that endurance training reduces Glycoside hemoglobin levels, the amount of strength training, although it did not significantly reduce, the strength training appears to cause more significant changes.
Endurance training
Strength training
Glycoside hemoglobin
Fasting plasma glucose
Diabetes
2011
12
01
75
81
http://yafte.lums.ac.ir/article-1-565-en.pdf
23-566
2024-03-29
10.1002
Yafteh
yafte
1563-0773
2981-0779
10.18869/acadpub.yafte
2011
13
3
Association of KIR-HLA interactions with diseases
Farhad
Shahsavar
Tahereh
Mousavi
tshabestari@sina.tums.ac.ir
Kobra
Entezami
Ali reza
Azargoon
The killer cell immunoglobulin-like receptors (KIR) are a recently discovered family of activating and inhibitory receptors which control natural killer (NK) cell function. KIR exist as a diverse family of receptors that have evolved rapidly by both gene duplication and recombination events. These findings were unexpected for a family of genes involved primarily in the innate immune response. Human leukocyte antigen (HLA) class I molecules serve as ligands for the KIR. Several disease association studies indicate a role for interactions between these loci in infectious diseases, autoimmune/inflammatory disorders, cancer and reproduction. Emerging functional data supports a mechanism based on a continuum of inhibition to activation through various compound KIR-HLA genotypes in diseases. This review summarizes the major features of these genes and discusses how they may be involved in both disease pathogenesis and its amelioration.
Innate Immunity
NK Cells
KIR
HLA
Disease
2011
12
01
82
96
http://yafte.lums.ac.ir/article-1-566-en.pdf
23-567
2024-03-29
10.1002
Yafteh
yafte
1563-0773
2981-0779
10.18869/acadpub.yafte
2011
13
3
IUD migration into bladder and stone formation on it
Mohamad
Haidari
mhaidari2010@yahoo.com
Abdolreza
Kheirollahi
Seyed saeed
Shahrokhi
Manochehr
Shams Khoramabadi
Background : Ectopic migration of IUD into bladder and urethra with subsequent formation of ston on it is among the rare complications of IUD .Two women, 38 and 45years old with recurrent bladder stone due to their IUDs inserted 5-6 years before were admitted with urinary irritation symptoms .In primary cystoscopy , no trace was found of either IUDs or their penetration into the stones . The stones were broken by electrohydraulic , however with further observation in the subsequent admissions and a thorough investigation , it was realized that the IUD prong had penetrated about 0.5 cm into bladder and formed stones . Since the IUDs could not be removed by cystoscope, in order to prevent the next recurrence and formation of cystovaginal fistula, the IUDs and stones were removed by cystostomy. In a two- year follow –up no complications were reported .
Migration
IUD
Stone
Bladder .
2011
12
01
97
102
http://yafte.lums.ac.ir/article-1-567-en.pdf