Background: Fungal infections in transplant recipient patients are among the main causes of mortality and disability due to immunosuppression. Involvement of the central nervous system because of fungal infections is one of the important and treatable factors in such patients. This study investigated a case of a 58-year-old diabetic patient with a history of kidney transplantation infected by cryptococcal meningitis 3 months after recovery from coronavirus disease 2019 (COVID-19) infection. A 58-year-old diabetic patient with a history of kidney transplantation presented with a complaint of prolonged headache, fever, nausea, and vomiting. The patient was admitted to the same center 3 months before with a diagnosis of COVID-19 infection. The examinations performed after cerebrospinal fluid sampling showed a slight reduction in the patient's neurological symptoms, and the analysis of cerebrospinal fluid and the use of Indian culture and ink demonstrated evidence of fungal infection. After treatment with Amphotericin and Flowocytosine, the patient was discharged from the hospital in a good general condition.