Volume 26, Issue 2 (6-2024)
yafte 2024, 26(2): 25-37 |
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Shakib P, Barfipoursalar A, haghighatian Z, Mohammadi R. Antibiotic Resistance Pattern of Klebsiella pneumoniae Strains Isolated from Patients Admitted to the Intensive Care Unit of Shahid Rahimi Hospital in Khorramabad in 2022. yafte 2024; 26 (2) :25-37
URL: http://yafte.lums.ac.ir/article-1-3709-en.html
URL: http://yafte.lums.ac.ir/article-1-3709-en.html
Pathology, Department of Pathology, Faculty of Medicine, Lorestan University of Medical Sciences, Khorramabad, Iran & Pathology, Department of Pathology, Faculty of Medicine, Lorestan University of Medical Sciences, Khorramabad, Iran
Abstract: (928 Views)
Background: Klebsiella pneumoniae is one of the essential types of human pathogenic bacteria. The emergence of antibiotic resistance has caused numerous treatment problems for its elimination. The present study aimed to assess the antibiotic resistance pattern of K. pneumoniae bacteria in patients admitted to the intensive care unit (ICU) of Shahid Rahimi Hospital in Khorramabad in 2022.
Materials and Methods: This cross-sectional descriptive study was conducted on 120 patients admitted to the ICU of Shahid Rahimi Khoramabad Hospital in 2022. After collecting K. pneumoniae isolates, the antibiotic resistance pattern of all isolates was evaluated. Thereafter, the relationship between antibiotic resistance and different variables was analyzed using SPSS software (version 25).
Results: In this study, the mean age of patients participating was 55.09±26.44 years. The most isolated strain of K. pneumoniae was obtained from urine samples (48.3%). The highest rate of antibiotic sensitivity was to amikacin (65.8%), gentamicin (50.8%), and ciprofloxacin (49.2%), while the highest rate of antibiotic resistance pertained to cefixime (68.3%), cefotaxime (66.7%), and ceftriaxone (60.8%). The pattern of antibiotic resistance showed a significant relationship with inpatient ICU, surgical ICU, general ICU, internal ICU, emergency ICU, and pediatric ICU (P < 0.05).
Conclusion: By specifying the pattern of antibiotic sensitivity in the ICU in the investigated area and reporting it to the doctors, the obtained results can be taken into account in experimental treatments, which in itself causes a better response from the patients to the received medicine and a reduction in antibiotic resistance in ICUs.
Materials and Methods: This cross-sectional descriptive study was conducted on 120 patients admitted to the ICU of Shahid Rahimi Khoramabad Hospital in 2022. After collecting K. pneumoniae isolates, the antibiotic resistance pattern of all isolates was evaluated. Thereafter, the relationship between antibiotic resistance and different variables was analyzed using SPSS software (version 25).
Results: In this study, the mean age of patients participating was 55.09±26.44 years. The most isolated strain of K. pneumoniae was obtained from urine samples (48.3%). The highest rate of antibiotic sensitivity was to amikacin (65.8%), gentamicin (50.8%), and ciprofloxacin (49.2%), while the highest rate of antibiotic resistance pertained to cefixime (68.3%), cefotaxime (66.7%), and ceftriaxone (60.8%). The pattern of antibiotic resistance showed a significant relationship with inpatient ICU, surgical ICU, general ICU, internal ICU, emergency ICU, and pediatric ICU (P < 0.05).
Conclusion: By specifying the pattern of antibiotic sensitivity in the ICU in the investigated area and reporting it to the doctors, the obtained results can be taken into account in experimental treatments, which in itself causes a better response from the patients to the received medicine and a reduction in antibiotic resistance in ICUs.
Type of Study: Research |
Subject:
میکروب شناسی
Received: 2024/02/18 | Accepted: 2024/06/29 | Published: 2024/08/24
Received: 2024/02/18 | Accepted: 2024/06/29 | Published: 2024/08/24
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