Yafteh

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Introduction: Coagulation disorders are among the diseases which afflict people and result in the death of a great number of them. Bleeding and increase of coagulation most of the time are endangers for many patients. The aim of this research was determination of PTT in urban population of Khorramabad. Materials & Methods: Through this study among 20-60 years old population living in Khorramabad city, 298 cases with no specific disease during testing, having negative history about coagulation or hemorrhagic disorders and in the mean time giving negative anti- coagulant drug history, were selected to detect their PTT value. All experiments have been done by Tilt- Tube Test at a reference lab through standard methods. More ever in order to reduce avaluation errors, all samples were tested by just a single person during the research time. Findings: In this study 298 individuals were experimented (149F, 149M). Incoming results showed that mean PTT value and its confidence limit in men were 13.44 sec & 33.97-34.91 respectively. In women, above PTT values were 34.59 sec & 34.97-35.12 respectively. In all samples, the mean PTT value equals 34.51 sec & 34.16-34.86 respectively. Comparing PTT value results in Khorramabad city showed that these values are significantly lower than those mentioned in reference books (pv<0.005). Conclusion: It is recommended that mean PTT value gained in this study should be presented to Khorramabad labs for their use.

Keywords: Intrinsic pathway, INR, PTT, Partial thromboplastin time

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