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Alavi A, Karimi S, Fallahi S, Akbari S, Alinejad A. A comparision of maintenance therapy and continuous intravenous therapy with magnesium sulfate in preterm labor pain management. yafte 2014; 16 (2) :64-70
URL: http://yafte.lums.ac.ir/article-1-1670-en.html

Background : The aim of this study was to compare maintenance therapy and continuous therapy of magnesium sulfate (MS) in the management of preterm labor. Materials and Methods: In this single blind randomized control trial, 70 singleton women in 26 to 34 weeks of gestation (WG), were randomly assigned to receive 4gr MS in 200cc D/W 5% during 15 to 20 minutes either infusion therapy with 20 gr MS in 10 hours (group A) or maintenance therapy with 2gr/hr MS for 12 hours.(group B). Data of the participants were collected and analyzed using SPSS13.0, Chi-Square and T test. P value less than 0.05 was considered statistically significant. Results: The presence of labor pain after 24 and 48 hours, 1 week, and in 34 WG was statistically lower in group B than A. But it was not statistically significant in 37 WG. Duration of pregnancy and Apgar score at 5 min were significantly higher in group B than A. While, NICU admission was higher in group A than B. Conclusion: Maintenance therapy with 2 mg/hr MS for 12 hr is an effective therapeutic regiment for management of preterm labor pain, to stop the labor pain, which is recommend to treat preterm labor pain.