Showing 11 results for najafi
Hasan Taymouri, Seyed Saeed Najafi, Zobeide Hatami,
Volume 5, Issue 1 (1-2004)
Abstract
Introduction: As endotracheal intubation is the first action which must be done for serious and very ill patients , so any procrastination leads to dangerous consequences including aspiration and finally death. Routine method for endotracheal intubation is injection of intravascular diazepam- Pethidine and sometimes muscle relaxants , but these drugs in Patients with GCS under 7 cause more decrease in level of consciousness.
Materials & Methods: In this clinical trial 60 patients who needed to intubation were divided into two groups of 30 patients randomly. The two groups were matched from view point of age, sex and weight.
In the experimental group before endotracheal intubation, bilateral supralaryngeal and transtracheal nerves were blocked by lidocain 2% .
In the control group, petidine – diazepam and lidocaine were administrated intravenously before intubation. Then the two groups were compared from view point of complications of intubation such as jaw resistance , vocal cord movement and bucking.
Finding : Statistical test showed that Jaw resistance , vocal cord movement and bucking in the experimental group were lower than control group .This difference was statistically significant (P<0.001).
Conclusion : According to the results, use of nerve block for intubation in Patients with GCS under 7 is suggested.
Hasan Teimori , Seyed Saeed Najafi, Hormoz Mahmoudvand , Mohammad Javad Tarrahi,
Volume 6, Issue 2 (8-2004)
Abstract
Background: Supraclavicular nerve block is a method for upper limb surgery in Anesthesiology. In this method that is common for supraclavicular block, injection anesthesia on the first rib and it has complications such as pneumothorax, phrenic never pulsy, infection, intra spinal injection. In this study injection with a 10 degree cephalic side as compared with the first rib in order to decrease of complications was evaluated.
Materials and methods: In this research with a interventional study on 100 patients injection was done with a 10 degree cephalic side to the first rib and incidence of these complications is 0% in the Z-test the statistical difference is significant.
Results: Results showed that there was no any case of peneumothorax and phernic nerve pulsy, although these complications were 6% and 60% in control group. There was significant in two groups using Z-test (p<0.0001).
Conclusions: Therefore in this method, incidence of pneumothorax and phrenic never pulsy is decreased. Suggested that this method and the other methods compare and use this method with more confidence.
Maziye Momen-Nasab , Seyed Saeed Najafi , Mohammad Hosein Kaveh , Farnaz Ahmad Pour ,
Volume 8, Issue 2 (1-2007)
Abstract
Background: Certain behaviors put people at high risk of premature death, disability or chronic diseases. The most common of such behaviors are smoking, bad eating habits, low physical activity, drug abusing and alcohol consumption, violent and injury and finally sexual high risk behavior. These behaviors are established during youth and extend to the adulthood. The aim of this study was to determine the prevalence of these behaviors among young people in Khorramabad.
Materials and methods: In this cross sectional study, 700 students were participated. The assessment tool was a two – part self administrated questionnaire, consisted of demographic data and questions in 10 parts. Data was analyzed with SPSS V9.6 by X2 and Fisher exact test.
Results: 67.1% of the students were female and 87.6% were single. The mean of their age was 21.26 years. 44.1% of them never used the seat belt of their cars. 13.9% had carried a weapon. 5.7% had an attempt for suicide. 25.1% of the university students had smoked cigarettes, 6% had drank alcohol an 8.3% had drug abuse. 32% of whom that experienced sexual intercourse had more than two partners and 39.8% of them had not used a condom. More than 90% had not eaten 5 servings /day of fruits and vegetables. More than 70 % had insufficient amount of physical activity.
Conclusion: Health education at national and local levels can reduce these behaviors among youth.
Bahram Delfan , Ali Ahmad Mosadegh , Salar Nasir Moghadas , Rezvan Batebi , Fatemeh Heidar Najafi , Maria Ahmadi ,
Volume 10, Issue 1 (yafteh 2008)
Abstract
Abstract Background: Medical errors are among the main problems of health and treatment in the world which are responsible for mortality and psychophysical complications in patients, families, and even in the society each year. Medical errors have been increasingly taken into consideration in different countries. Different strategies have been explored to prevent medical errors, one of which is undergraduates education. The aime of this research is to study the current status and the necessity of medical errors education as one of the curricula from viewpoint of general practitioners in Lorestan province graduated from different universities. Materials and methods: A questionnaire was designed and distributed among 200 GPs in Lorestan province to be completed, then data were analyzed using SPSS software. Results: The results of the survey indicated that 90% of the GPs have not been taught any courses entitled medical error prevention. Moreover, 64% had committed medical errors before graduation, out of which 47.5% had been diagnostic errors. Additionally, 60% has committed medical errors after graduation, out of which 51% has been errors in disease diagnosis. 72.5% of them stated that have not taken any education about medical errors after graduation, 88.5% considered medical error prevention education as essential, and 40% believed that the education have to be restricted to diagnostic errors. Conclusion: Regarding the results of the present study and the importance of the topic, teaching medical error prevention as separate credits is highly recommended for medical students, as well as GPs need to be taught related education.
Shirin Hasanvand, Seyed Saeid Najafi, Mansore Forozy, Sakine Mohammad Alizade , Dr Ali Akbar Haghdoost,
Volume 12, Issue 3 (3-2011)
Abstract
High blood pressure is a disorder associated with stress. In numerous people, behavioral strategies or stress management interventions such as relaxation and massage are useful in control of their response to stress and consequently , the reduction of blood pressure. Regarding to more effects of combinational intervention therapy based on behavioral methods rather than application of pharmacotherapy , it is expected that the use of these methods including massage is more effective in decreasing blood pressure. Materials and Methods: In this quasi-experimental,based on pilot study, 90 hypertensive patients were chosen and their blood pressure and radial pulse were measured in 20 sessions during 5 weeks before and after back massage on Saturdays and Tuesdays and without massage on Sundays and Wednesdays . Data were collected by a demographic questionnaire and check list to record blood pressure and pulse, then these data were analyzed by STATA software. Results: The results showed that there was a decrease in the systolic and diastolic blood pressure and radial pulse by 6.3 and 3.9 mmHg and 2.9 beats per minute (p=0.0001). Conclusion: The results revealed that massage had decreasing effect on blood pressure and pulse of the primary hypertensive patients . Use of stress management interventions such as massage is an acceptable, simple and teachable method to families for better control of the disease.
Ebrahim Falahi, Ayda Najafi, Porya Tondkar, Masome Karami, Sajad Roosta,
Volume 17, Issue 4 (2-2016)
Abstract
Background : Past studies have shown that dairy intake have an inverse association with metabolic syndrome. Although the underlying mechanism is not completely clear, it seems that vitamin D and calcium are two main factors responsible for this positive association.
The aim of this study was to determine the association between dietary calcium intake and vitamin D and metabolic syndrome and its components.
Materials and Methods: In this cross sectional study, 973 individuals (237 males and 736 females) from the residents of Khorramabad were selected using randomized multi-stage cluster sampling method. Dietary intakes of people, by use of a food frequency questionnaire (201 items), were evaluated and using Nutritionist 4 software were analyzed. Venous blood samples were collected to measure the metabolic variables and blood pressure were measured .Metabolic syndrome according to American Heart Association (AHA) criteria was defined.
Results: The findings showed that there is a significant relationship between marital status and metabolic syndrome (p=0.001). Also there is a significant relationship between education and risk of metabolic syndrome (p=0.001).
There was a significant inverse correlation between vitamin D and increased TG, FBS and SBP, (p=0.018, p=0.04, p=0.026 respectively) but there was no relationship between calcium and metabolic syndrome components.
Conclusion: There was no significant association between vitamin D dietary and metabolic syndrome, although between vitamin D intake and the risk of high levels of FBS, TG and SBP inverse relationship were shown, although there is no significant relationship between calcium intake and metabolic syndrome.
Mosa Darvish Sargazi , Sadigh Sabbagh, Hamid Reza Miri, Shala Najafi, Kazem Sabbagh,
Volume 17, Issue 4 (2-2016)
Abstract
Background: With respect to antioxidant effect of Prosopis farcta fruit extract and the role of antioxidant agents in diabetes improvement, the aim of this study was to investigate the effect of hydro-alcoholic Prosopis farcta fruit extract on blood glucose and gene expression of pyruvate kinase (PK).
Materials and Methods: Type 1 diabete was induced in male wistar rats (150-300 g) by injection of 60 mg/kg of streptozotocin. Diabetic group received 300 mg/kg of Prosopis farcta fruit extract daily 30 days. The group of normal control and diabetic control received distilled water. Then the glucose level was investigated in day before injection and on days 15 and 30 after injection of prosopis farcta fruit extract. PK gene expression of liver tissue was analysed by Real-Time PCR.
Results: The result showed the blood glucose compare to diabetic control significantly decreased on days 15 and there was not any significant between diabetic control. The result of PK gene expression showed that the gene expression in diabetic treatment group compared to diabetic control increased on day 15 and then the expression did not change on day 30 but still wars greater than diabetic control.
Conclusion: The result of this study showed that hydro-alcoholic prosopis farcta fruit extract could probably decrease blood glucose by increasing PK gene expression.
Mehdi Shahkarimi, Ali Shalizar Jalali , Mehdi Behfar, Gholam Reza Najafi,
Volume 19, Issue 1 (6-2017)
Abstract
Background : Ischemia-reperfusion injury arising from testicular torsion can result in bilateral testicular damages. The aim of this study was to investigate the effect of doxycycline (DC) administration on epididymal sperm disorders following experimental unilateral testicular ischemia-reperfusion (IR) in mice.
Materials and Methods: Experiments were performed on five equal groups each comprising six adult male mice. Following anaesthesia, IR was induced by clamping left testicular vessels with an atraumatic microvascular clamp for 30 minutes in IR group. In IR+DC group, in addition, mice received DC (2.5 mg/kg per day) intraperitoneally for 3 days starting from the day of induction of experimental IR. Vehicle-treated control group, sham-operated control group and DC-only treated group were also included. Ipsilateral and contralateral epididymal sperm characteristics were evaluated after 35 days.
Results: Ischemia-reperfusion caused significant decreases in the both epididymides sperms concentration, viability and motility compared to the control group. Moreover, sperm cell apoptosis in both the ischemic and the contralateral epididymides and the percentage of sperm abnormality in ipsilateral epididymis increased significantly after IR. Doxycycline treatment attenuated all IR-induced negative changes in the above-noted parameters.
Conclusion: These findings provide evidence that DC treatment may have potentially protective effects against long-term reproductive injuries following unilateral testicular IR.
Mahmood Najafian, Mohammad Javad Nowroznejhad, Amir Arasteh, Zahra Najafian, Bahareh Najafian,
Volume 19, Issue 4 (10-2017)
Abstract
Background: Ibuprofen is a nonsteroidal anti-inflammatory medication of drugs that is used for relieving pain. However, this drug has proven effects, such as the production of free radicals and interfering with cellular events. Thus, it is necessary to find suitable antioxidants to reduce the side effects of this drug. In this study the antioxidant effects of cinnamon extract on the inhibition induced hepatoxicity of ibuprofen has been investigated.
Materials and Methods: 48 rats in six groups, S group received saline solution, C200 group received cinnamon extract 200mg per kg body weight (200mg/kg b.w), I group ibuprofen 400mg/kg b.w, IC50 group ibuprofen together with cinnamon extract 50mg/kg b.w, IC100 group ibuprofen together with cinnamon extract 100mg/kg b.w, IC200 group ibuprofen together with cinnamon extract 200mg/kg b.w intraperitoneally. The activity of liver enzymes were measured in the end of the experimental period. Liver tissue sample was prepared and after staining with hematoxylin-eosin, was studied.
Results: The activity of Pyruvate transaminase, oxaloacetate transaminase and alkaline phosphatase in I group in comparison with S group were significantly increased. The activity of these enzymes in IC50, IC100 and IC200 groups in comparison with I group were significantly decreased nearly in a dose dependent manner. Examining the liver tissue indicate tissue damage caused by ibuprofen, and cinnamon consumption was reduced tissue destruction.
Conclusion: Cinnamon extract has antioxidant properties and reduces the ibuprofen induced hepatoxicity.
Asghar Mohammadi, Reza Hosseini-Fard, Hasan Ghasemi, Behnam Alipour, Amene Yarnazari, Parisa Hasanpour, Abazar Roustazadeh, Mohammad Najafi, Azim Shams Beiranvand, Abdolah Amirfarhangi,
Volume 19, Issue 5 (2-2018)
Abstract
Background: Coronary artery stenosis is one of the atherosclerotic complications which can lead to decreased oxygen supply in heart tissue and heart attack. rs1050450 Polymorphism is one of polymorphisms in GPx1 gene that may change its antioxidant activity. Furthermore, two polymorphisms of NADPH Oxidase, rs4673 and rs13306294, are suggested to have a role in the function of this enzyme. In this study, we examined the rs1050450, rs4673 and rs13306294 polymorphisms in the patients with coronary artery stenosis.
Materials and Methods: 190 angiography subjects are subdivided into two groups (patients (n =114) and control (n =76)). Lipid profile and polymorphic sites were measured by routine laboratory tests and RFLP-(ARMS) PCR, respectively.
Results: In this study we, observed the significant difference between serum LDL level and degree of stenosis. Also, we observed significant difference for rs13306294 polymorphism between patients and controls. On the controlling age, gender and BMI, no correlations were observed between rs13306294, rs1050450 and rs4673 polymorphisms and coronary artery stenosis (P<0.05).
Conclusion: rs13306294, rs4673 and rs13306294 polymorphisms have not a basic role in the progression of coronary artery stenosis.
Marzieh Momennasab, Razieh Nouzari, Seyede Saeid Najafi ,
Volume 23, Issue 2 (5-2021)
Abstract
Background: Diagnosis of cancer is a traumatic experience. But cancer patients may have some positive experiences that are called post traumatic growth (PTG). The aim of this study was to determine the rate of post-traumatic growth in cancer patients and its relationship with social support and hope.
Materials and Methods: The present descriptive correlational study was conducted during May-August 2018 in Shiraz, Iran. Population included of 112 all adult patients with gastrointestinal cancer who referred to medical centers affiliated to Shiraz University of Medical Sciences. Data collection instruments included a demographic information form, post-traumatic growth inventory, social support appraisals scale, and Miller hope scale. The data were analyzed by SPSS software (version 23.0). P<0.05 was considered statistically significant. Analytical data were analyzed using the Pearson correlation coefficient, sample t test, one-way analysis of variance independent and multiple regression analysis. In the case of non-normal distribution, the equivalent nonparametric analysis was used.
Results: The mean score (SD (for PTG was 81.37)15.64(which is considered as high level. The mean score (SD) for hope, and SS was 195.20 (24.92), and 97.39 (11.37), respectively. A significant positive correlation was found between PTG and both hope (r=0.687, P˂0.05) and SS (r=0.636, P˂0.05). The results of the multiple regression analysis showed a significant relationship between PTG, SS, and hope (P˂0.05). According to multiple regression analysis hope had a higher effect on PTG (ẞ=0.613) compared to SS (ẞ=0.192).
Conclusion: The results showed a good level of PTG among the cancer patients. Regarding the association between PTG with the perceived SS and hope, health care providers can help their patient by hope instillation and providing social support.
