Showing 4 results for Cardiovascular Diseases
Masoume Sadeghi, Pezhman Aghdak , Ramin Heidari, Sedighe Dehghan Naseiri , Rezvan Ghaheri, Mostafa Cheraghi , Nazal Sarrafzadegan ,
Volume 13, Issue 4 (3-2012)
Abstract
Background : The aim of the study was to evaluate the relationship between main CVD risk factors and healthy life style of housewives and working women.
Materials and Methods: The current study was a part of the Isfahan Healthy Heart Program (IHHP). Data sampling was stratified multistage sampling in the women over 20 years old. Demographic information, nutritional status as Global Dietary Index (GDI), physical activity and smoking status were recorded. Blood pressure, anthropometric indicies, total cholesterol, LDL-c and HDL-c, TG, FBS were detected. Collected data were processed by T -test, chi square and logistic regression.
Results: 5591 (92%) out of 6102, were housewives and the rest were working women.The nutritional status in working women was worse than the housewives. In contrast, the physical activity was better in working women. There were no significant differences between two groups regarding smoking. After adjusting for age, BMI, Lipid profile and blood pressure were the same in the both groups. Dyslipidemia, diabetes and obesity were not significantly different between two groups.
Conclusion: Regarding the results, a more comprehensive interventional program for healthy lifestyle and risk factors should be carried out.
Nazal Sarrafzadegan , Katayon Rabiei , Masoume Sadeghi , Mozhgan Gharipour, Mohammad Hosein Hosieni , Behzad Zolfaghari , Mostafa Cheraghi , Abas Feizbakhsh, Ali Mostofi , Sonia Zarfeshani ,
Volume 14, Issue 1 (6-2012)
Abstract
Background : Healthy Life for Cardiovascular Patients(HLCP), one of the ten projects included in Isfahan Healthy Heart Program, was designed and performed based on high-risk and secondary prevention strategies and aimed to reduce cardiac recurrences, along with the risk factors, morbidity and mortality among cardiovascular patients. In this study we investigate the trend of changes of frequency of coronary patients’ medicine intake, aswell as the results of process evaluation.
Materials and Methods: Five main strategies were designed to meet the project's goals. These interventions were designed based on education, legislation, and attracting inter-division and public cooperation. Process evaluation was performed in order to determine the project's successfulness. Prior to the project, the morbidity and medicine intake among the patients were also studied. These indices were again measured during the interventions and also after the project were completed.
Results: Amongst all the interventions, educating the patients during the hospitalization period, at the time of release and also post-release educations were successful. Another success of the project in merging secondary prevention programs in the society was to attract public coordination and to establish a Non-Governmental Organization. The results also show an increase in the amount of aspirin, beta blockers, Angiotensin Converting Enzyme (ACE) Inhibitors, and statins taken by cardiovascular patients during the project.
Conclusion: The results suggest that secondary prevention and cardiovascular patient care promotion interventions can be performed using available facilities.
Mehrnoosh Sedighi, Mostafa Cheraghi, Pejman Hashemzadeh,
Volume 23, Issue 0 (11-2021)
Abstract
Background &Objective: Despite the fact that public awareness about diabetes control and cardiovascular diseases has increased, but still the main cause of morbidity and mortality in the community. For the treatment and control of diabetes and heart disease can be pharmacological and nonpharmacological methods used. The purpose of this review study is to introduce several risk factors in diabetic patients that increase the chances of cardiovascular involvement.
Materials and Methods: In this review study, Pubmed, ISI and Scopus databases were used to search for articles during the years 1979 to 2020, and the keywords of blood pressure, oxidative stress, obesity, dyslipidemia, endothelial function and inflammatory factors were used.
Results: The worldwide prevalence of diabetes and the occurrence of serious and dangerous complications on the organs of the body, has made this disease a major health problem in all communities and is the main cause of cardiovascular disease. Our study showed that cardiovascular disease is the most common cause of death in diabetic patients. Factors associated with diabetes and cardiovascular disease include high blood pressure, oxidative stress, obesity, dyslipidemia, endothelial function, and inflammatory factors.
Conclusion: Diabetes is a major cause of cardiovascular disease. Cardiovascular disease is also the most common cause of death in diabetics.
Mohsen Ghiasi, Abdolreza Dayani,
Volume 27, Issue 1 (12-2025)
Abstract
Background: Cardiovascular diseases (CVD) are considered the leading cause of mortality worldwide. According to World Health Organization statistics in 2022, these diseases resulted in the deaths of nearly 19.8 million people globally. The early diagnosis and timely treatment are among the main challenges in managing these diseases. Generally, since some of the currently used biomarkers lack specificity; therefore, a stronger need for more specific markers in this area is felt. Exosomes, as one of the extracellular vesicles, are produced in almost all eukaryotic cells. These microvesicles are covered with a bilayer phospholipid membrane and carry proteins, nucleic acids, lipids, etc.
Materials and Methods: The current narrative review research included studies available in the international databases of PubMed, Scopus, and Web of Science.
Results: Various factors, including stress, cellular damage, medications, and toxins can influence the production and secretion of exosomes. Exosomes play a crucial role in intercellular communications and can serve as biological markers for diagnostic and prognostic strategies. Additionally, exosomes have therapeutic potential and act as biological carriers for targeted drug delivery to the heart.
Conclusion: Based on the findings obtained, the use of the exosomes in the diagnosis and treatment of cardiovascular diseases could aid in the better management of these conditions; however, its application may be clinically challenging. Moreover, the present study explores the potential of using exosomes as a novel tool in the medical field.
