Showing 8 results for Lipid Profile
Esmaeel Yossefi-Rad , Javad Mohtadi-Nia , Akbar Ali , Asgarzadeh ,
Volume 11, Issue 2 (4-2009)
Abstract
Background: Studies indicate that there might be relations between the level of chromium in body and risk factors of diabetes. The purpose of this study is to investigate the relation between the food intake and serum level of chromium with the lipid profile, HbA1c, and glucose in patients with type 2 diabetes.
Materials and Methods: The subjects under investigation consist of 30 patients (15 females, 15 males) aged 30-60, with type 2 diabetes and a control group of 30 non-diabetic people (15 female, 15 males).They were matched for age, gender and BMI. From each participant, a 3-day 24-hour food recall was filled. Moreover, blood sample was taken to measure blood levels of sugar, HbA1c, lipid profile and chromium.
Results: The mean of serum chromium in diabetic group was 0.80 ± 0.28 μgr/dl and 1.19 ± 0.33 μgr/dl in control group, hence significantly lower in diabetic
group(P < 0.001). Dietary intake of chromium was not significantly different between the two groups. The correlation test indicated that there was no significant association between serum level of chromium and its dietary intake with fasting blood sugar (P = 0.706), HbA1c (P = 0.927), serum level of TG (P = 0.663), total cholesterol (P = 0.707), HDL-C (P = 0.209) and LDL-C (P = 0.365).
Conclusion: There was significant difference in the serum level of chromium between the diabetic group and control group although there existed no difference between dietary chromium intake of them. This is probably due to the increase of urinary excretion of this element in the diabetics.
Somaye Saboori , Mohammad Javad Hosseinzadeh , Mostafa Hoseini , Esmaeel Yousefi Rad ,
Volume 14, Issue 4 (12-2012)
Abstract
Background : Some studies have shown that the serum concentration of 25- hydroxy vitamin D which is represent the status of body vitamin D, has a diverse relationship with obesity status, and the risk of obesity decreases in people with high level of 25- hydroxy vitamin D. The aim of this study is to investigate the correlation between the serum level of 25- hydroxy vitamin D and anthropometric indices, glucose, lipid profile, serum insulin, and insulin resistance in obese women.
Materials and Methods: This study was carried out on 43 obese women and 43 healthy women with normal weight as a control group, aged 20-50. They were matched for age and physical activity. For each participant, a 3-day 24-hours food recall was filled. Moreover, fasting blood sampling was taken to measure blood levels of fasting blood glucose, 25- hydroxy vitamin D, lipid profile and serum insulin.
Results: The mean level of serum 25- hydroxy vitamin D, insulin and also insulin resistance based on IR-HOMA index in the group of obesity and control were 28.05 ± 16.66 versus 25.72 ± 14.08 (P=0.48 ) , 25.97 ± 7.53 versus 25.93 ± 9.32 (P=0.98 ) , and 6.39 ± 2.6 versus 5.83 ± 2.5 (P=0.30) respectively. Between the anthropometric indices, 25- hydroxy vitamin D had a significant relationship only with body weight in obese group (p=0.033, r= 0.326 ). No significant relationship was observed between serum 25- hydroxy vitamin D with blood sugar, lipid profile, serum insulin level and HOMA-IR in obese women.
Conclusion: No significant relationship was seen between serum level of 25- hydroxy vitamin D with anthropometric indices (except for body weight), serum levels of glucose, lipid profile and insulin resistance in the obese women.
Soheila Akbari , Parvin Asti , Azin Alavi , Noshin Amjadi ,
Volume 14, Issue 5 (2-2013)
Abstract
Background: Even though hormonal changes in pregnancy have been associated with plasma lipid variation, is not yet understood the mechanism which pregnancy alters lipid metabolism.
Materials and Methods: This prospective cohort study conducted between March 2011 and May 2012 in Shariati Hospital on 112 pregnant women with GDM and 159 healthy pregnant women. In order to determine lipids or lipoproteins changes during pregnancy lipid components, glucose and insulin levels were obtained in maternal serum three times in the third trimester.
Results: Maternal serum glucose, total cholesterol (TC), low and high density lipoprotein (LDL-c, HDL-c) levels did not show any significant difference between two groups. While insulin, homeostasis model assessment-insulin resistance (HOMA-IR) and triglyceride (TG) values were detected to be significantly higher in the GDM cases especially after32weeks of gestation (P<0.05) and according to spearman test the increase of TG level was correlated with increase of insulin resistance and HOMA-IR (PV=0.001).
Conclusion: Due to positive correlation of hypertriglyceridemia and hyperinsulinemia, it is possible to assume that elevated TGs levels in GDM cases is a reflection of variation in maternal insulin levels.
Hasan Ahmadvand , Ali Khosrowbeygi , Gholamreza Shahsavari , Maryam Hormozi , Foad Abdolahpour , Shahrokh Bagheri ,
Volume 16, Issue 4 (2-2015)
Abstract
Background: The prevalence of diabetes is rising in the world. The aim of this study was to determine the possible protective effect of sodium selenite on serum lipid profile and atherogenic indexes in Alloxan-induced Type 1 diabetic rats. Materials and Methods: Forty Sprage-dawley male rats were divided into four groups randomly group one, as control, group two, sham (control treated with sodium selenite (1mg/kg)), group three, diabetic untreated, and group four, treated with sodium selenite (1mg/kg), respectively. Diabetes was induced in the second and third groups by alloxan injection subcutaneously. After 8 weeks, animals were anaesthetized, blood samples were also collected before killing to measure the blood glucose, triglyceride, cholesterol, LDL, VLDL, HDL and serum atherogenic indexes. Results: Sdium selenite inhibited a significant decrease of BG, TG, C, LDL and VLDL. HDL level. Sodium selenite inhibited significantly serum atherogenic indexes level. Conclusion: This study showed that sodium selenite exerts beneficial effects on the BG, lipid profile and atherogenic indexes in alloxan-induced Type 1 diabetic rats.
Samira Babaeian Amini, Mehrangiz Ebrahimi Mameghani , Mitra Niafar,
Volume 18, Issue 3 (12-2016)
Abstract
Background : Diabetes mellitus is one of the prevalence metabolic disorders in the worldwide. Studies have shown that fruits, vegetables and drinks that are rich in phenolic and antioxidants components may reduce cardiovascular and diabetes diseases. One of these fruits is Pomegranate that is rich in phelavonoid. Therefore, this study was designed to determine pomegranate juice effect on fast blood sugar, lipid profile, anthropometry, total antioxidant capacity and blood pressure in diabetic patients.
Materials and Methods: In the present study, 50 patients with diabetes aged 30-50 were recruited into the study and randomly assigned into 2 groups:1) intervention group (n=25) that fed 240cc pomegranate juice daily, 2) control group (n=25) that fed 240cc water daily. Weight, hip circumstance, waist circumstance, lipid profile (HDL-C, LDL-C, TG, TC) glucose, HbA1C, GPX, total antioxidant capacity, systolic and diastolic blood pressure were measured at the baseline and end of 8 weeks.
Results: Insulin resistance, systolic and diastolic blood pressure, body weight, hip circumstance, waist circumstance decreased significantly and GPX increased in intervention group whereas pomegranate juice had no significant effect on glucose, HbA1C, lipid profile and total antioxidant capacity.
Conclusion: These findings indicate that beneficial effect of pomegranate juice on insulin resistance, systolic and diastolic blood pressure, body weight, hip circumstance, waist circumstance, GPX
Mahdieh Piri, Mohammad Reza Batavani, Mohsen Ghofrani, Omid Mohammaddoost,
Volume 24, Issue 1 (4-2022)
Abstract
Background: Trampoline rebound is one of the recent interesting exercises. The present study aimed to investigate the effect of six weeks of trampoline rebound exercises on cardiovascular indices, body mass index, and lipid profile of obese and overweight women.
Materials and Methods: The statistical population of the present quasi-experimental study consisted of 20 obese and overweight women in Zahedan ( (BMI) ≤27.5 kg/m2), and randomly assigned to two groups of exercise (n=10) and control (n=10). The subjects participated in four 90-min sessions of rebound trampoline exercises for six weeks using a trampoline mat. Physiological, BMI, and lipid parameters were measured in two stages of pre-test and post-test. Data were analyzed in SPSS software (version 21) using independent and dependent t-test, as well as an ANCOVA test. A p-value less than 0.05 was considered statistically significant.
Results: The results demonstrated a significant decrease in post-test values of LDL (from 92.90±1.52 to 73.10±3.81), cholesterol (from 182.10±1.96 to 166.30±6.32), triglyceride (from 108.30±1.33 to 95.30±5.35), and body mass index (29.44±1.07 to 27.38±1.02), as well as a significant increase in HDL (from 59.60±2.75 to 77.00± 3.09) and Vo2max (from 45.50±1.31 to 57.80±1.31) in posttest of the training group, compared to their pre-test (P<0.05). Furthermore, there were the same changes in these parameters in the exercise group, compared to the post-test values of the control group (P<0.05).
Conclusion: As evidenced by the results of this study, six weeks of trampoline rebound training had beneficial effects on controlling lipid profile, cardiovascular indices, and body mass index of obese and overweight women. This training protocol is suggested to improve these indicators in the same groups with obesity and overweight, especially for the variety of exercises.
Hamidreza Zolfi, Amir Shakib, Adel Valipour,
Volume 24, Issue 2 (7-2022)
Abstract
Background: Prediabetes is an important risk factor for developing type 2 diabetes and cardiovascular diseases. The current study aims to investigate the changes in miR-204 and serum glucose following eight weeks of high-intensity interval training (HIIT) in the men with prediabetes.
Materials and Methods: In this quasi-experimental study with a pre-test/post-test design, 24 middle-aged men (aged 40-50 years) with prediabetes (Fasting blood sugar= 110-125 mg/dL) were randomly assigned to the training and control groups. The training group performed the HIIT (High Knee, Butterfly, Burpee, Kettlebell Snatch, and Scott Goblet) with an intensity of 80-90% of heart rate for eight weeks (three sessions in the first four weeks and four sessions in the second four weeks). The blood samples were taken from the subjects 48 hours before and after the last training session to analyze the level of miR-204, lipid profile, and the serum glucose level. Data were analyzed by using paired t-test and ANCOVA in SPSS v.25 software, considering a significance level of P˂0.05.
Results: The eight weeks of HIIT significantly reduced the serum levels of miR-204 (P=0.001), Triglyceride (P˂0.001), Cholesterol (P˂0.001), low-density lipoprotein (P˂0.001), and glucose (P=0.031) compared to the control group. Furthermore, after HIIT, a significant increase in the serum high-density lipoprotein level was observed (P˂0.001).
Conclusion: It seems that miR-204 is an appropriate indicator for regulating the blood glucose level in both diabetic and pre-diabetic men. Furthermore, HIIT can reduce the lipid profile by altering the expression of miR-204 and, subsequently, reducing the glucose level.
Somaieh Sabzali, Seifollah Bahramikia, Kiana Shahzamani,
Volume 26, Issue 4 (10-2024)
Abstract
Background: An increase in blood fat, especially cholesterol, is one of the chronic diseases that are caused by metabolic disorders caused by many factors. Due to the side effects and harmful effects of chemical drugs, the issue of returning to the use of herbal and natural drugs has received serious attention nowadays. Therefore, the present study aimed to introduce and review different formulations of herbal extracts whose effectiveness in the reduction of blood lipid profile has been proven.
Materials and Methods: The studies conducted in this field were reviewed in the form of a narrative review article.
Results: It is noteworthy that the desire to use medicinal plants that reduce blood fat has become widespread in most societies, even in developed countries. The consumption of these plants is especially significant when common treatments are not able to control the disease.
Conclusion: Although the arbitrary consumption of medicinal plants by patients with high blood fat may improve the disease, there is a possibility of drug interaction with common drugs, and because its use is irregular and with an uncertain and variable dose, it may cause a disturbance in disease control. Therefore, if it is intended for use, the treating physician must be informed.
