Showing 3 results for Specificity
Mojtaba Ahmai Nejad , Mozhgan Saki,
Volume 13, Issue 4 (3-2012)
Abstract
Background : The acute inflamation of appendix is called appendicitis which is one of the most common surgical emergencies. Appendicitis must be diagnosed and appendectomy should be done. In order to prevent appendix gangrene or other complications such as peritonitis, phelegmon and abscess. Since sonography as an accurate diagnosis method to evaluate pathological processes has been accepted for every organ of the body, so among all diagnostic measurments, it along with other clinical symptoms has an immense role to dignose appendicitis. The purpose of this study is to determine the sensitivity and specificity of sonography to the diagnosis of appendicitis in suspected patients referred to Ashayer hospital in khorramabad in 2005.
Materials and Methods: This descriptive cross-sectional study included all suspected individuals with acute appendicitis referred to the hospital during 5 months. The data gathered through a questionnaire, physical examination and surgery done by specialist and the sonography results which were compared with pathoelogy results. The data were analysed using descriptive statistics and SPSS software. Comparing the results of sonography and pathology, the positive and negative cases were recognized. The sesitivity and specificity of sonography was recognized too.
Results: Among 131 suspected cases, 6 cases had negative sonography,their symptoms improved,so they were cured and were excluded from the study. Among 125 patients, 88 cases (%70.4) had positive sonography and 37 (%29.6) had negative sonography. Through comparison between results of sonography and pathology , 72 cases were true positive patients, 16 cases were false positive patients. 12 cases were true negative patients. 25 cases were false negative patients. Also the sensitivity and specificity were 74% and 43% respectively.
Conclusion: As the study suggests, sonography before sugery can help and leads to definite diagnosis in suspected patients to appendicitis and it can prevent unnecessary surgeries, as well as it can prevent delay in treatment and related complications .
Tayebeh Rezaie Nasab , Eraj Salehi , Mosa Kafie , Sajad Rezaei , Shahrokh Yousefzadeh ,
Volume 14, Issue 5 (2-2013)
Abstract
Background: Bender Gestalt Test is one of the most famous neuropsychological tests, simple and easy to perform, and is used to evaluate brain injuries. This study aimed at determining the rate of sensitivity, characteristic and cut-off point of this test in patients with traumatic brain injury (TBI).
Methods and Materials: Overall, 120 TBI patients with mean age of 31.25± 13.60 years old in a descriptive-analytical research design entered the study using nonprobability and consecutive sampling method. All patients underwent Bender Visual-Motor Gestalt Test after neurological evaluations by CT scan. Roc curve test was utilized to analyze the data.
Results: In this study, cut-off point was calculated as 6.5%, sensitivity as 55.8%, characteristic as 81.2%, and the area under the Roc curve as 0.69. Moreover, positive predictive value, negative predictive value and efficiency were 95.08%, 22.03%, and 59.17%, respectively.
Conclusion: Results of this study revealed that Bender Gestalt Test is relatively weak in diagnosis of mild TBI. Hence, its characteristic is high and it was successful in diagnosing healthy individuals.
Hooman Hanifehpour, Shirzad Fallahi, Fatemeh Ashrafi, Elham Siasi,
Volume 26, Issue 4 (10-2024)
Abstract
Background: Rapid, accurate, and specific molecular diagnosis of SARS-CoV-2 virus is essential to prevent and fight against corona disease, therefore, the purpose of this research is to investigate the diagnostic value of LAMP (Loop-Mediated Isothermal Amplification) molecular technique in rapid evaluation and obtaining accurate results and reducing the costs of corona testing compared to other routine molecular methods.
Materials and Methods: The results showed, 342 nasopharyngeal samples were collected from reference medical centers in Tehran. In the next step, RNA was extracted from the samples. After designing the primer for the N gene, an RT-LAMP assay was performed. To confirm the results, LAMP products were electrophoresed on agarose gel. Also, the RT-LAMP technique was evaluated in terms of sensitivity and specificity. SPSS version 22 software was used for statistical analysis of the results.
Results: In the present study, the statistical analysis of the data showed that there is a significant difference between the gender variable and the severity of the disease (P>0.001, while there was no significant difference in terms of the age variable (P>0.05). In terms of clinical symptoms, the relationship There was a substantial difference between the severity of the virus infection with the symptoms of fever, cough and headache (P>0.001. Also, statistically, a significant difference was observed between diabetes and the severity of the disease (P>0.001) in terms of the sensitivity and specificity of the RT-LAMP technique., the sensitivity of this dilution technique was 101x1 and the specificity was 100%.
Conclusion: Fast and timely diagnosis of the Corona virus is very important due to the high rate of spread of the virus. Therefore, there is a need for a fast and cheap diagnostic method that can be performed in different places and is affordable with high sensitivity and specificity. Based on the results obtained from the present study, the RT-LAMP technique is a fast, sensitive, and effective method for diagnosing SARS-CoV-2.
