Volume 15, Number 1 (5-2013)                   yafte 2013, 15(1): 59-70 | Back to browse issues page


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Miraghajani M S, Esmaillzadeh A, Mortazavi M, Mirlohi M, Azadbakht L. Soy milk consumption, inflammation, coagulation and oxidative stress among type 2 diabetic patients with nephropathy. yafte. 2013; 15 (1) :59-70
URL: http://yafte.lums.ac.ir/article-1-1190-en.html

Food Security Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
Abstract:   (7447 Views)
Background : Nephropathy is a common complication of diabetes and it is the major cause of disability and death among these patients. We aimed to determine the effects of soy milk on inflammation, coagulation and oxidative stress among type 2 diabetic patients with nephropathy. Methods: This randomized crossover controlled clinical trial was conducted on type 2 diabetic patients with nephropathy. This study had two trial phases, each for 4 weeks and one washout period for two weeks. Patients were randomly assigned to consume a diet containing soy milk, or a diet containing cow’s milk. Results: Soy milk consumption, in comparison to cow’s milk, resulted in a significant reduction in D-dimer level. This significant effect remained even after adjustment of cofounding factor (carbohydrate intake). However, soy milk consumption had no significant effects on inflammation and oxidative stress levels. Conclusion: Soy milk consumption for 4 weeks could decrease serum D-dimer level in type 2 diabetic patients with nephropathy.
Full-Text [PDF 234 kb]   (1411 Downloads)    
Type of Study: Research |
Received: 2013/05/12 | Accepted: 2013/05/19 | Published: 2013/05/19

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