Volume 15, Issue 5 (3-2014)                   yafte 2014, 15(5): 104-111 | Back to browse issues page

XML Persian Abstract Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Aliashrafi S, Ebrahimi-Mameghani M, Irandoost P, Hamzavi F. Serum ferritin and liver enzymes ratio and their agreement with NAFLD severity. yafte. 2014; 15 (5) :104-111
URL: http://yafte.lums.ac.ir/article-1-1498-en.html
Abstract:   (12856 Views)
Background : Non-Alcoholic Fatty Liver Disease (NAFLD) is the most common liver disease. NAFLD is characterized by elevated liver enzymes and serum ferritin concentration due to damage and abnormal function of liver cells. Increased level of serum ferritin as a parameter of liver function is commonly observed .The aim of this study was to determine the agreement between serum liver with liver and ferritin echogenicity in NAFLD patients. Materials and Methods: This cross-sectional study was carried out on 60 NAFLD patients confirmed by ultrasonography in Tabriz. Fasting blood samples were taken for assessment of Alanin aminotransferase, Aspartat aminotransferase and ferritin level. Weight and height were measured. Liver enzymes ratio were estimated and classified into tertile. Results: The mean of serum ferritin was126.34±108.25 ng/ml and was significantly associated with severity of liver echogenisity (p=0.016). Significant relationship was observed between fatty liver severity and ALT/AST ratio (p=0.004) with good agreement (Kappa value= 68.3%) while the ratio of ferritin to liver enzymes was not significantly associated with the severity of NAFLD. Conclusion: This study suggests significant agreement between severity of fatty liver and ferritin and liver enzymes ratio in NAFLD patients but not with the ratio of ferritin to liver enzymes.
Full-Text [PDF 197 kb]   (14236 Downloads)    
Type of Study: Research |
Received: 2014/03/1 | Accepted: 2014/03/1 | Published: 2014/03/1

Add your comments about this article : Your username or Email:

Send email to the article author

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

© 2022 CC BY-NC 4.0 | Yafteh

Designed & Developed by : Yektaweb