Background : Less phenomenon, such as addiction has threatened the human societies. Despite the risks and complications of addiction, victims of this deadly trap are added every day. So we decided to study the causes of tendency to opium substances in patients with the diagnosis of drug poisoning and addiction in educational hospitals of Khorramabad city. Materials and Methods: A descriptive epidemiologic study on 100 patients diagnosed with addiction and intoxication with informed consent conducted in 2014. The research instrument was a questionnaire consisting of two parts, the first part of the information on individual characteristics and the second was to determine the factors associated with opioid use in patients, the questions in the field of employment, economic, educational, family and social factors. After data collecting, statistical analysis was performed. Results: 11 females and 89 males were studied, and the most frequent age group was 30-39 years. 81% were urban and 19% rural. Enjoyment and physical capacity for work, to get rid of the problems of life, relieve mental and neurological disorders, colored with bad friends, unemployment, low cost and availability of opiates, were the most common causes of fendency to substance use. Conclusion: Individual, familial, economic and social factors coordinated toward substance use. It is hoped that the results of this study to increase the awareness of officials and planners in the policy implementation and provide preventive and controlling measures to prevent addiction and its consequences.
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