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Masoumi Jouibari S, Barahman M, Panahi M, Nikoofar A, Sayad S. Investigation of relapse and the measure of tumor free safe margin in the breast cancer patients undergoing breast conservation surgery: A descriptive study in Firoozgar center of Tehran (2016-2018). yafte. 2021; 23 :161-169
URL: http://yafte.lums.ac.ir/article-1-3153-en.html
Department of Surgery, Firoozgar Clinical Research Development Center (FCRDC), Iran University of Medical Sciences, Tehran, Iran
Abstract:   (414 Views)
Introduction: Breast cancer is the most common cancer in Iran based on age standardized incidence. Multidisciplinary approach including surgery, pathology, chemotherapy and radiotherapy in treatment of this cancer is of a great importance. In this study, we intend to investigate 2-year relapse free survival and the measure of tumor free safe margin in the breast conservation surgery patients undergoing multidisciplinary treatment.
Methods: This study was conducted in Firoozgar hospital of Tehran. Patient were imported to the study by census from May 2016 to September 2018 and followed up by September 2020. For the patients, superior, inferior, lateral, medial, anterior and deep margins were measured in lumpectomy samples. In addition, 2-year relapse was reported based on Poisson distribution.
Results: In this study, 156 cases were initially selected by census that 81 of them were breast conservation surgery. The mean of safe margin was 1.73 superior, 2.02 inferior, 2.30 lateral, 2.41 medial, 1.49 anterior and 1.27 deep. Only one case of local recurrence was observed (relapse free survival = 98.77%).
Conclusion: Enough safe margin along with a multidisciplinary treatment approach was associated with the 98% relapse free survival which was more than previous studies. It seems that lower amounts of margin could also be associated with lower recurrence, but it is more important to use specialists of different majors to manage the patients. This approach is suggested to be used in future.
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Type of Study: Research | Subject: جراحی
Received: 2021/01/6 | Accepted: 2021/08/1 | Published: 2021/12/1

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