Volume 13, Number 1 (6-2011)                   yafte 2011, 13(1): 1-6 | Back to browse issues page


XML Persian Abstract Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

ahmadvand H, tavafi M, shahsavari G, Khosrowbeygi A, Abdolahpour F, bagheri S et al . The effects of Coenzyme Q10 on serum lipid profile in male rats diabetic. yafte. 2011; 13 (1) :1-6
URL: http://yafte.lums.ac.ir/article-1-387-en.html

Assistant Professor Lorestan University of Medical Sciences, Khorramabad, Iran
Abstract:   (11482 Views)
The prevalence of diabets in the world is rapidly rising. Currently over 180 million persons worldwide have diabets and this number is expected to be doubled in the year 2030. In diabets stress oxidative markrs are increased. Coenzyme Q10 as a potent antioxidant can decrease lipid peroxidation and deplete free radicals. The persent study investigated the effects of coenzyme Q10 on serum lipid profile in male Wistar rats diabetics quantitatively. Material and Methods: Twenty one male rats (200-250 gr) were randomly used in tree groups for the experiments(7 rats per group). First group as control, second group as untreated diabetic and third group as treated diabetic with Coenzyme Q10 (15 mg/kg). Second and third groups were diabetic with injection of alloxan(120 mg/kg). After six weeks treatment their serum lipids,were measured. Data were analyzed using SPSS software. Data were compared by Mann Whitney test. Results: The results indicated that Coenzyme Q10 decreased serum triglyceride , cholesterole , LDL and VLDL in treated diabetic groups in comparision with untreated diabetic groups respectively, but serum HDL didn't increase(P<0.05). Conclusion: Regarding the fact that Coenzyme Q10 decreases serum lipids. Our data suggest that Coenzyme Q10 has beneficial effects on diabetes induced complications.
Full-Text [PDF 643 kb]   (1686 Downloads)    
Type of Study: Research |
Received: 2011/06/11

Add your comments about this article : Your username or email:
Write the security code in the box

Send email to the article author


© 2015 All Rights Reserved | Yafteh

Designed & Developed by : Yektaweb