Volume 27, Issue 1 (12-2025)                   yafte 2025, 27(1): 1-13 | Back to browse issues page

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Sari-Sarraf V, Vakili J, Fakhri Kaleybar M. Effect of eight weeks of high-intensity interval training on red cell distribution width and mean platelet volume in inactive normal-weight and obese women. yafte 2025; 27 (1) :1-13
URL: http://yafte.lums.ac.ir/article-1-3757-en.html
Department of Exercise Physiology, Faculty of Physical Education and Sport Sciences, University of Tabriz, Tabriz, Iran & Department of Exercise Physiology, Faculty of Physical Education and Sport Sciences, University of Tabriz, Tabriz, Iran
Abstract:   (531 Views)
Background: The predictive role of mean platelet volume (MPV) and red cell distribution width (RDW) in cardiovascular diseases has been proven. High-intensity interval training (HIIT) is a sustainable and effective method for improving cardiorespiratory fitness. Therefore, the present study aimed to investigate the effect of eight weeks of HIIT on MPV and RDW in inactive, normal-weight, and obese women.
Materials and Methods: In this semi-experimental research, 24 participants were voluntarily selected from a population of inactive, healthy, obese women and healthy women of normal weight aged 30 to 45 years. They were divided into two experimental groups, each consisting of 12 participants (normal-weight and obese). Both groups were in a circuit HIIT protocol for eight weeks, three sessions per week with an intensity of 90% HRmax for related exercises. Blood sampling was taken on two occasions: once before and once after a 12-hour fasting period and again 48 hours after the last training session. The analysis of covariance (ANCOVA) statistical test was employed to analyze variables at a significance level of P < 0.05.
Results: The results indicated that there was a statistically significant difference between the two obese and normal weight groups in the average decreases in MPV (P=0.045), red blood cell distribution width (RDW) (P=0.001), and high-density lipoprotein (HDL) (P=0.045).
Conclusion: High-intensity exercise may modulate MPV and other cardiovascular disease risk factors, such as high body mass index and high body fat percentage in middle-aged women, suggesting an effective, inexpensive, and accessible non-pharmacological method for reducing the risk of cardiovascular diseases.
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Type of Study: Research | Subject: قلب و عروق
Received: 2024/08/6 | Accepted: 2024/11/27 | Published: 2025/03/4

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