Amene Mahmoodi, Elham Shahabpoor, Mustafa Moradi Sarabi, Sedigheh Tahmasebi, Maryam Koushkie Jahromi,
Volume 21, Issue 3 (11-2019)
Abstract
Background: Breast cancer and its treatments induce various physical complications, including cardiovascular problems. Exercise training is one of the recommended methods for preventing or reducing these complications. The purpose of this research was to evaluate the impact of 8 weeks of Pilates exercises on cardiovascular indices in breast cancer patients.
Materials and Methods: This study was a randomized clinical trial. Participants of the study included 30 female breast cancer patients who participated in the study voluntarily. They were randomly divided into two groups of the exercise (n=15) and the control (n=15). The exercise group performed Pilates exercise for 8 weeks, 3 days a week, for 60 min per session, but the control group did not participate in any regular physical activity. The resting heart rate and systolic as well as diastolic blood pressure were measure using a blood pressure monitor device prior to and after the training period of the both groups. Subsequently, the rate pressure product and the resting systolic heart rate were separately multiplied by resting heart rate. Analysis of covariance statistical test was used to carry out data analysis.
Results: Pilates exercises decreased systolic blood pressure (P<0.035), heart rate (P<0.02) and rate pressure product (P<0.003) in breast cancer women, but did not have any effect on their diastolic blood pressure (P<0.18).
Conclusion: Women with breast cancer are recommended to perform Pilates exercises for the improvement of their cardiovascular indices.
Mahsa Yadsar, Elham Shahabpoor, Mustafa Moradi Sarabi, Maryam Koushkie Jahromi,
Volume 23, Issue 3 (8-2021)
Abstract
Background: Hepatocellular damage caused by physical activity or the use of supplements is one of the serious problems facing athletes in various fields. This study aimed to evaluate the effect of different doses of nitric oxide supplements on AST and ALT liver enzymes and the ratio of AST to ALT following a session of eccentric exercise in Sprague Dawley male rats.
Materials and Methods: In this study, 36 Sprague Dawley male rats (two months old) were divided into three groups of control, low dose (4.8 mg/kg body weight), and high dose of NO supplements (15.4 mg/kg body weight). Supplements were given to rats for seven days. Subsequently, all three groups of rats were forced to run on a treadmill for 45 min with a speed of 20 m/min, and a slope of -15 degrees. Blood samples were taken directly from cardiac puncture of rats 24 h after the running exercise. Blood serum variables of the study were measured afterward.
Results: Low dose of nitrate supplements did not change AST and ALT indices, while the high dose of nitrate supplements increased ALT serum level and decreased AST to ALT ratio, compared to a low dose of NO supplements and control group.
Conclusion: Based on the obtained results, the consumption of a low dose of NO supplements does not change hepatocellular damage markers, while the high dose of NO supplements causes degeneration of hepatic cells in athletes.
