Showing 4 results for Sabzali
Somaye Sabzali , Salar Bakhtiyari , Arman Rostamzad , Karime Haghani ,
Volume 15, Issue 2 (8-2013)
Abstract
Background : Nerium oleander is used to cure several diseases in China and the Arabs, ancient medicine. This study tried to investigate the anti-bacterial activities of the hydroalcoholic extract of Nerium oleander which is native of Ilam province.
Materials and Methods: Nerium oleander was collected from the Zagros mountains, Ilam province, Iran. After naming and identification, the plant extract was provided by the maceration method. The Pothogenic bacteria were effected by different concentrations of the extract using the disc diffusion method. Diagnostic antibiotics were used as positive control. MIC and MBC were also determined.
Results: The maximum effect of Nerium oleander’s hydroalcoholic extract was found in the concentration of 76 mg/ml. The maximum zone of inhibition in 76 mg/ml concentration was related to E. faecalis 2321 bacterum, and the minimum zone of inhibition was related to P. aeruginosa in the same concentration. In determining MIC and MBC, it was found that S. aureus1885 had the lowest MIC in 5 mg/ml concentration, and E. coli and P. aeruginosa showed the highest MIC in 76 mg/ml concentration.
Conclusion: The results showed that positive gram bacteria were more sensitive to Nerium oleander extract than negative gram bacteria. According to the bacteria’s zones of inhibition, it can be concluded that hydroalchohalic extract of Nerium oleander has a considerable anti-bacterial effect on the bacteria under the investigation.
Somaye Sabzali , Salar Bakhtiyari , Karemeh Haghani , Arman Rostamzad , Kyana Shahzamani ,
Volume 16, Issue 2 (9-2014)
Abstract
Background: Treatment of bacterial diseases by synthetic antibiotics leads to problems such as side effects in human and antibiotic resistance in microorganisms. Recently, plants have been given more attention in curing bacterial diseases. Since the use of Thymbra spicata is common in Iranian ancient medicine, this study tried to investigate the antibacterial effects of the extract of Thymbra speculate on some gram positive and gram negative pathogenic bacteria.
Materials and Methods: The mentioned plant was collected from Zagros mountains, Ilam province, Iran. After naming and identification, the plant extract was provided by the maceration method. The bacteria were affected by different concentrations of the extract using the disc diffusion method. Diagnostic antibiotics were used as positive control and DMSO as negative control. MIC and MBC were also determined.
Results: The highest effect of the extract was found in gram positive bacteria. The maximum zones of inhibition were observed in 76 mg/ml concentration of the extract, and S. aureus and S. epidermidis were more sensitive than other bacteria (P˂0.05). The lowest MIC was pertaining to S. aureus (1885) with 2.5 mg/ml and S. epidermidis (2405) with 5mg/ml of extract. E. coli and K. penemonia with 15 mm zone of inhibition were the most sensitive gram negative bacteria to the extract.
Conclusion: The hydroalcoholic extract of T. spicata had a considerable antibacterial effect. Statistic assessment of the inhibition zones showed that the extract was more effective on gram positive bacteria
Somaieh Sabzali, Kiana Shahzamani, Hamzeh Hasani, Mehdi Birjandi,
Volume 26, Issue 2 (6-2024)
Abstract
Background: The presence of microbial agents on different hospital surfaces is considered a harmful factor to health. The use of hypochlorous acid (HOCl) for health purposes has been evaluated in more than 50 countries. The present study aimed to assess the disinfection effect of Sanitizon solutions and common disinfectants (Sayasept HP and Sayasept 420) on the reduction of microbial load in Shohada-ye Ashayer Hospital, Khorram Abad.
Materials and Methods: In this experimental study, 200 samples from intensive care units were prepared and studied in seven experimental groups (one control group and six different types of disincentives) in six different hospital departments. The samples were cultured on specific culture media. The results were analyzed using SPSS software (version 23). The germicidal power of disinfectants was investigated according to standard 10504 and diffusion method in agar.
Results: The use of disinfectants caused a significant decrease in the microbial load compared to the control group. Disinfection solutions led to a decrease in the number of colonies from 113 to 12. Moreover, all disinfectants had germicidal and fungicidal power according to the standard (reduction of four logarithms of bacteria). The Sanitizon solution succeeded in removing all microorganisms and reducing more than seven logarithms of test microorganisms. Sanitizon caused a more marked reduction of gram-negative bacteria and fungi compared to other disinfectants.
Conclusion: As evidenced by the results, Sanitizon can be used along with other common disinfectant products to clean surfaces. The intermittent use of disinfectants with different active substances reduces the probability of resistance in microorganisms.
Somaieh Sabzali, Seifollah Bahramikia, Kiana Shahzamani,
Volume 26, Issue 4 (10-2024)
Abstract
Background: An increase in blood fat, especially cholesterol, is one of the chronic diseases that are caused by metabolic disorders caused by many factors. Due to the side effects and harmful effects of chemical drugs, the issue of returning to the use of herbal and natural drugs has received serious attention nowadays. Therefore, the present study aimed to introduce and review different formulations of herbal extracts whose effectiveness in the reduction of blood lipid profile has been proven.
Materials and Methods: The studies conducted in this field were reviewed in the form of a narrative review article.
Results: It is noteworthy that the desire to use medicinal plants that reduce blood fat has become widespread in most societies, even in developed countries. The consumption of these plants is especially significant when common treatments are not able to control the disease.
Conclusion: Although the arbitrary consumption of medicinal plants by patients with high blood fat may improve the disease, there is a possibility of drug interaction with common drugs, and because its use is irregular and with an uncertain and variable dose, it may cause a disturbance in disease control. Therefore, if it is intended for use, the treating physician must be informed.
