Showing 8 results for safari
Safar Shams , Mohammad Reza Safari ,
Volume 7, Issue 2 (8-2005)
Abstract
Background: Free radicals and reactive oxygen species(ROS) are the most important factors in formation of oxidative stress reaction. Now, radical damage has been suggested to contribute to a wide variety of diseases such as Alzheimer, atherosclerosis and cancer. Transition metal ions in the presence of the various biomolecules produce these active compounds. The aim of this study is introducing a new and rapid method for measuring of ROS.
Materials and methods: In this cross-sectional study, the amount of free radical production by transition metal ions such as iron, copper and vanadium in the presence of the thiol group-containing glutathione and cysteine(as reducing agents) and molecular oxygen was measured in vitro by thiobarbitturic acid(TBA) test. For measuring free radicals levels, the suger deoxyribose was used as a detector molecule. Attack of free radicals on deoxyribose produces a number of aldehyde compounds such as malondialdehyde(MDA). Then, MDA was combined with TBA as a detector, which makes a chromogen with maximum absorption at wavelength 532nm. Also, the effects of vitamin C and E on the radical production by these metal ions were studied.
Findings: Vanadium was considerably more effective than iron and copper (Pvalue<0.05) to generate free radicals. The generation of free radicals by iron and copper was depended on the presence of glutathione or cysteine in medium(for Fe-glutathione system was 0.611±0.039 and for Cu-cysteine system was 0.592±0.033). Vitamins C and E had an inhibitory effect on the radical production by three metal ions that were used (Pvalue < 0.05). Specially, vitamin C in 100 micromolar concentration had the greatest effect on free radical formation(83% Inhibition with
P value < 0.05).
Conclusions: These results suggest that reaction of transition metals with thiols in the presence of oxygen, generate ROS, and vitamin C and E inhibit free radical production.
Dr Ali Reza Aghayosefi, Kobra Moradi, Nosh Afarin Safari, Shirin Ghazi, Fatemeh Amiri,
Volume 13, Issue 1 (6-2011)
Abstract
Thepsycho-physiological disorders are the real physical symptoms that created by emotional factors or may be worse by their effect. Evidences show that psychological status in humans cause immunity changes and disease. If the response to stress makes us susceptible to physical disease, so stressful events must be frequently associated with disease. Pregnancy and childbirth for most women is associated with high stress. During pregnancy many changes take place in emotions and communication of people , marital satisfaction in this period can influence on intensity of maternal stress and associated with physical and mental disorders for her.
Therefore this study investigated the relationship between marital satisfaction and problems during pregnancy and whether these psychological factors are related to intensity of problems during the pregnancy or not?
Materials and Methods: Descriptive correlational method was used to carry out this study. The statistical society of this study is all of the pregnant women of khorramabad referred to health-medical centers in Summer (209). For data gathering, 2 of 15 health-medical centers were randomly selected and then from each center 20(40 total) with the help of midwife and using simple random sampling were selected and simultaneously Enrich marital satisfaction questionnaire with 11 subscales and the questionnaire of common physical problems during the pregnancy performed on the subjects. Obtained information were analyzed using correlation, regression, T test and ANOVA.
Results: 1- There is a reverse and significant relation between current problem of pregnancy periods and the main score of matrimonial satisfaction.
2 – There is a positive and significant relation between current problems of pregnancy periods and variables such as womans, age and age difference between man and woman .
3- The women with MA, and secondary degrees have low matrimonial satisfaction in comparison with the women with diploma and bachelors, degree.
Conclusion: Based on the results and according to importance of the effect of stress during pregnancy on physical and mental health of mother, it is recommended to couples to increase their marital satisfaction, to reduce the stress of mothers and reduce the physical problems during pregnancy.
Abdolrahim Yusefzadeh , Ghodratollah Khorramabadi Shams , Hatam Godini , Edris Hoseinzadeh , Mehdi Safari,
Volume 15, Issue 5 (3-2014)
Abstract
Background : Rivers are a fraction of flowing waters in the worlds and one of the important sources of water for different consumptions such as agricultural, drinking and industrial uses. The aim of this study was to assess water quality of the Khorramrood River in Khorramabad by NSFWQI index. Materials and Methods: In this cross-sectional study, quality parameters needed for NASWQI index calculation such as BOD5, dissolved oxygen (DO), total nitrate, fecal coliform, pH, total phosphate, temperature, turbidity and total suspended solids content were measured for six months (from July to December 2012)using standard methods at six selected stations. The river zoning conducted by GIS software. Results: According to the results obtained through this study, the highest and the lowest water quality value was observed in stations 1 and 6 with NSFWQI indexes 82 water with good quality, 42 water with bad quality, respectively. With moving toward last station (from 1 to 6 station) water pollution increased. Conclusion: Results of the study indicated that water quality index NSFWQI is a good index to identify the effect of polluter sources on the river water. Based on the average of the index NSFWQI, water quality in station one was good, in the second, third and fourth stations were mediocre and the fifth and sixth stations had bad quality. These results allow to make decisions about monitoring and controlling water pollution sources, as well as provide different efficient uses of it by relevant authorities.
Nooshafaren Safari , Ali Abas Miraghaei , Sheren Ghazi , Kobra Moradi ,
Volume 16, Issue 2 (9-2014)
Abstract
Background: The main purpose of this study was to investigate the relationship between adherence to prayers and mental health among the students of Khorramabad Payame Noor University in Khoramabad.
Materials and Methods: The method of the study was correlation analysis. The population of the study was all the students of Khorramabad Payame Noor university. The sample size comprised of 400 students, based on Morgantable, were selected using proportional stratification sampling method. Data gathering instruments were Panahi’s (2003) adherence to prayers questionnaire and Geldberg and Healer’s (1979) general health questionnaire (GHQ). The reliability of the questionnaire of adnerence to prayers was found to be 0.906 and for the general health questionnaire was 0.95. The descriptive statistics of frequency, percentage, percentile and Pearson’s correlation coefficient were used in this study.
Results: The results showed that 68.7% had a very high, 26.5% had a high, 3.8% had a Mediocre, and only 1% had a low or very low adherence to prayers. Based on the study results, 47.5% of the samples had no or little disorder in their mental health. 33.3% showed middle mental health disorder, 14.5% had a mediocre disorder in mental health, 4.7% showed severe mental health disorder. The results showed that there is a significant relationship between adherence to prayers and mental health in terms of general mental health as well as any other micro measures of mental health.
Conclusion: Thus, according to this study by adopting suitable methods the mental health rate of students can be promoted. Adopting cultural programs to boost adherence to prayers in elementary school students can increase mental health in later years.
Hosein Zare , Kobra Moradi , Sheren Ghazi , Nooshafaren Safari , Razeh Lotfi ,
Volume 16, Issue 3 (1-2015)
Abstract
Background: As we can not process all the information, we should select the information which is of great importance for us. It seems that patients with anxiety disorders, draw selective attention to stimulants which are associated with those disorders and ignore other information. Thus, the purpose of this study is a comparison of selective attention among patients with depression, obsessive, anxiety, and normal individuals. Materials and Methods: This paired comparison study carried out on all normal individuals and patients with depression, anxiety and obsessive- compulsive referred to psychiatric clinic of Lorestan university of medical sciences in 2012. 120 patients (30 cases with depression, 30 anxiety, 30 obsessive - compulsive and 30 normal) were selected using convenience sampling method. To measure selective attention, the Stroop test (color test - word) was used. The descriptive indicators (frequency, mean, standard deviation) and inferential test of Scheffe were used for multivariate analysis. Results: The results showed that depressed individuals, response speed is slower than the other 3 groups. Also anxiety and obsessive patients compared to normal ones have slower response speed, but show faster reaction than the depressed people. As well as, the results showed that depressed individual have more erros in comparison with normal people, but no significant difference was doserved between other groups in this field. Conclusion: Based on the obtained results and regarding the importance of application of selective attention in everyday life, it is recommended put a lot of effort to increase slective attention in these patients.
Farhad Ariamanesh , Farideh Malekshahi , Mehdi Safari ,
Volume 17, Issue 1 (5-2015)
Abstract
Background : Studies have shown, about 20 to 80 percent of hemodialysis patients have sleep problems that can lead to reduction of their quality of life. With regard to high number of hemodialysis patients in the present age, promoting the level of their health issues are deemed important. In this regared, the purpose of this research was to determine the effect of foot massage on night sleeping in hemodialysis patients. Materials and Methods: This experimental clinical trial design, was conducted on 80 hemodialysis patients, admitted to the hemodialysis wards of Shahid Rahimi and Shohada hospitals of Khorramabad city in 2014. Data gathering was done by Pittsburg questionnaire and Sleep Log, by which the sleep condition of the subjects was assessed before and after the night of massage therapy. The treatment was Stroke Foot Massage, carried out during dialysis for 10 minutes, three times a week, for four consecutive weeks. Results: Changes in the Pittsburg questionnaire score indicated that, using foot massage can improve sleep quality of hemodialysis patients and sleep hours increased and generally sleep condition was progressively improving each week than the week before (p<0/001). Conclusion: According to the results of this study, foot massage has a favorable impact on sleep quality in hemodialysis patients undergoing hemodialysis and can be applied and trained as a useful method to improve sleep quality of patients in hemodialysis wards.
Ghodratollah Roshanaei , Javad Faradmal , Malihe Safari , Alireza Soltanian , Sanambar Sadighi ,
Volume 17, Issue 2 (9-2015)
Abstract
Background : Surgery is the most important treatment in gastric cancer (GC) patients and also chemotherapy and radiotherapy are used as adjuvant and/or neo-adjuvant therapies for reducing locally relapse and metastasis. This study aimed to compare patients' survival and affected factors in this two treatment groups. Materials and Methods: This historical cohort study was conducted on 181 patients underwent chemotherapy (group 1) and 201 patients underwent surgery (group 2). The effect of demographic, clinical and pathological risk factors on patients' survival was assessed by log-rank test and Cox Proportional Hazard (CPH) model. Data were analyzed using SPSS16. Results: Fifty and six patients (30.6%) in surgery group and 69 patients (34.3%) in chemotherapy group passed atoay death by the end of the study. The median survival time in two groups was 19 and 28 months, respectively. Age at diagnosis and tumor grade in surgery group, and gender and pathologic stage in chemotherapy group were significant (p<0.05). Conclusion: Demographic and pathological characteristics of patients are the significant determinant of treatment success and increasing survival, however, assessing the causal effect of treatments on survival will be well achieved via controlled clinical trials through which the effects of confounders can be controlled.
Saba Safari, Seifollah Bahramikia, Faranak Hadi, Hadis Asadolahi, Shima Mostaed, Fatemeh Zarini,
Volume 25, Issue 2 (8-2023)
Abstract
Background: In the present study, the solvent effect (aqueous and hydroalcoholic) of the extraction on the content of phenol, flavonoid, and the antioxidant activity of six medicinal plants, including Persian oak fruit hull (Quercus brantii), Zataria multiflora, German Matricaria chamomilla, Teucrium polium, Rosa foetida Herrm, and mountain barberry (Berberis integerrima) was investigated.
Materials and Methods: To measure phenol and flavonoid content, folin ciocaltio and aluminum chloride reagents were used, respectively, and to measure the antioxidant potential, the DPPH method was used. The content of phenol and flavonoid compounds was calculated as mg equivalent of gallic acid and catechin per gram of dry weight of the plant, respectively. The collected data was analyzed in SPSS software (version 14).
Results: According to the obtained results, the amount of phenol and flavonoid in the hydroalcoholic extract of oak fruit hull Quercus brantii, Zataria multiflora, German Matricaria chamomilla, and mountain barberry was more than the aqueous extract, and this difference was statistically significant (P<0.001). The highest content of phenol and flavonoid were related to the hydroalcoholic extract of oak by 310.2 ± 2.5 mg/g and 241.2 ± 1 mg/g, respectively, and the lowest amounts were related to the aqueous extract of Matricaria chamomilla (53.1±1.1 mg/g) and the aqueous extract of acorn (23.9±1.5 mg/g), respectively. The highest antioxidant activity (IC50) was related to oak fruit-hull hydroalcoholic extract (39.1±4.4 µg/ml), and the lowest was related to the aqueous extract of Matricaria chamomilla (315.3±3.3 µg/ml).
Conclusion: The findings of this study showed that the solvent used to extract plants is a significant factor in separation of phenol and flavonoid compounds as well as their antioxidant activity.
