Showing 37 results for Saki
Dr Shahram Khademvatan, Dr Rasol Jamali, Jereel , Dr Jasem Saki,
Volume 13, Issue 1 (6-2011)
Abstract
The purpose of quality control program was to make doctors and laboratory personnel trust in laboratory results and consequently increasing confidence in laboratory achievements. The quality assurance means raising the level of quality in all tests that lead to raising the level of work efficiency and laboratories including minimum expense for society and minimum time for lab personnel. This study aimed to assess and determine the accuracy and precision of results in Tabriz medical diagnostic laboratories. Materials and Methods: In this retrospective study, 790 stool samples were selected randomly and tested by standard methods.Student t- test, SPSS software and sensitivity and accuracy formulas were used for data analysis. Results: The sensitivity was 62%, 22% and 8% with 95% confidence intervals for worm's eggs, protozoan cysts and trophozoite detection respectively. Conclusion: To elevate quality assurance in clinical diagnostic laboratory, monitoring and check of the laboratories by standard methods continually should be done.
Mandana Saki, Dr Mozhgan Jariani, Dr Hedayat Nazari, Moammad Javad Tarahi, Mohammad Gholami, Mozhgan Saki, Behroz Ezatpoor,
Volume 13, Issue 1 (6-2011)
Abstract
Depression disorder is one of the most common mental diseases which causes psychiatric frequent disabilities . As results of researches imply that there exists a relationship between Omega3 and depression , we decided to do the present study to investigate the effect of Omega3 on depression .
Materials and Methods: The present study is a clinical trial which included 80 patients selected randomly . The subjects were interviewed by a psychiatrist and Beck inventory was administered to measure the degree of their depression .The data were collected and analyzed .
Results: The findings indicated that the average grade obtained from Beck inventory in the both groups treated with Omega3 and Nortriptyline during a 3- month period was decreased remarkably . Also the patients 'performances improved during this period . Statistical
Analysis showed a significant relationship among average grade in Beck inventory and performance level gained by the patients.
Conclusion: Based on the research findings and the proved effects of Omega3 on the treatment of depression , it is recommended that these should be prescribed for non psychotic depression as the first stage of treatment .
Hedayat Nazari, Mandana Saki, Masoume Zareai Dehno , Mehdi Birjandi,
Volume 13, Issue 3 (12-2011)
Abstract
Background : Drug abuse and addiction is a social and medical burden which has drastic
consequences in the community. There has been various rehabilitative and healing programs
for the addicts.The conducted studies have shown that therapeutic community treatment
model is an appropriate method for restoring the addicts to society. The present study tries
to evaluate the impact of TC treatment programs on the addicts’ personality characteristics.
Materials and Methods: This interventional study includes all the male addicts for whom
the detoxification period has been finished. The subjects were selected using easy random
sampling method form clients referred to TC center. At the beginning of the study , SCL90
questionnaire was filled out by psychologist for each sample, then 60 cases were selected
based on the sample size formula. The subjects participated in a training TC program for
three months daily except weekends. At the end of a three-month program, SCL 90 was
given to the subjects to be completed and the data were gathered and analyzed.
Results: The results showed that the subjects before entering the study were: 16.7% normal
,40% border personality disorder ,30% sick and 13.4% very sick. After intervention of TC
,25% normal ,66.7% with suspicious,8.3% sick. None of the cases were highly sick after
the TC intervention.The mean of the marks for personality disorders before the TC
intervention was 2.4± 0.92,after the intervention it was 1.83 ± 0.56.The Willcoxson rating
test showed a significant difference between the severity of personality disorders before and
after the TC intervention(p<0.001).
Conclusion: As it was mentioned in the findings, the implementation of TC intervention
had a significant effect on the scores obtained for personality disorder. So administrators
and policy makers who are responsible for addiction control are recommended to develop
and support the centers for Therapeutic Community and endeavour to provide a life without
narcotic substances.
Mozhgan Jariani , Mandana Saki, Nahid Momeni, Farzad Ebrahimzade, Ali Seydian,
Volume 13, Issue 3 (12-2011)
Abstract
Background : Coronary and artery diseases are amongst the most common existed diseases in human societies. Thus considering too much stress that is created after myocardial infarction and the effect which anxiety can have on the treatment process of
myocardial infraction patients, This research was carried out to study the effect of applying progressive muscle relaxation of these patients.
Materials and Methods: This clinical trail study was done on sixteen patients with myocardial infarction afflicted to the disease two weeks before the beginning of the research.After selecting qualified samples , the patients were divided into two groups of intervention and control. Both groups were matched from view points of age, sex, and the amount of anxiety. In the first day, for each group the cattle anxiety questionnaire was completed and their vital signs were recorded, and then for the intervention group the progressive muscle relaxation technique was done during 3 sequential days and on the whole in 6 sessions. And again after 3days variables were measured. The gathered data were analyzed by SPSS software.
Results: In the intervention group anxiety, systolic and diastolic blood pressure had a significant decrease comparing to the control group (P<0.001),while decrease was not significant in the control group.
Conclusion: progressive muscle relaxation can reduce the amount of anxiety, and systolic and diastolic blood pressure of the patients with myocardial infarction hospitalized in CCU ward, therefore it can play an effective role as a supplement non-medicinal, simple and cheap treatment for these patients
Mojtaba Ahmai Nejad , Mozhgan Saki,
Volume 13, Issue 4 (3-2012)
Abstract
Background : The acute inflamation of appendix is called appendicitis which is one of the most common surgical emergencies. Appendicitis must be diagnosed and appendectomy should be done. In order to prevent appendix gangrene or other complications such as peritonitis, phelegmon and abscess. Since sonography as an accurate diagnosis method to evaluate pathological processes has been accepted for every organ of the body, so among all diagnostic measurments, it along with other clinical symptoms has an immense role to dignose appendicitis. The purpose of this study is to determine the sensitivity and specificity of sonography to the diagnosis of appendicitis in suspected patients referred to Ashayer hospital in khorramabad in 2005.
Materials and Methods: This descriptive cross-sectional study included all suspected individuals with acute appendicitis referred to the hospital during 5 months. The data gathered through a questionnaire, physical examination and surgery done by specialist and the sonography results which were compared with pathoelogy results. The data were analysed using descriptive statistics and SPSS software. Comparing the results of sonography and pathology, the positive and negative cases were recognized. The sesitivity and specificity of sonography was recognized too.
Results: Among 131 suspected cases, 6 cases had negative sonography,their symptoms improved,so they were cured and were excluded from the study. Among 125 patients, 88 cases (%70.4) had positive sonography and 37 (%29.6) had negative sonography. Through comparison between results of sonography and pathology , 72 cases were true positive patients, 16 cases were false positive patients. 12 cases were true negative patients. 25 cases were false negative patients. Also the sensitivity and specificity were 74% and 43% respectively.
Conclusion: As the study suggests, sonography before sugery can help and leads to definite diagnosis in suspected patients to appendicitis and it can prevent unnecessary surgeries, as well as it can prevent delay in treatment and related complications .
Fatemeh Saki , Mandana Beigi Boroujeni , Meh Angiz Sadoughi , Omid Ali Adeli ,
Volume 14, Issue 3 (9-2012)
Abstract
Background: Aspirin is a non steroidal medicine that effects on prostaglandin, follicles, ovulation and corpus luteum. The aim of this study was to evaluate the effect of low (7.5 mg/kg) dose of Aspirin on the ovarian tissue during implantation period.
Materials and Methods: Females NMRI mice 6-8 weeks old were divided into control and experimental groups. These groups were rendered pseudopregnant then experimental group injected with low dose of Aspirin until 4.5th day. The mice were scarified with cervical dislocation and then the samples were obtained from the ovary in each group. Then ovarian weight and volume balance were measured and paper section stained with H&E method.
Results: Our results showed that weight of ovary in control group was 3.1±0.077g and in experimental group was 3.5±0.24g (p<0.05). Volume of ovary in control group was 8.70±0.19 mm3, and in experimental group was 9.20±0.17 mm3 (p<0.05). Number of corpus luteum in control group was 6.2±0.15, and in experimental group was 12.21±0.15 (p<0.05). In experimental group vascularity of ovary had increased in comparison with control group.
Conclusion: The low dose of Aspirin (7.5mg/kg) increased the rate of corpus luteum and vascularity of ovary . Low dose of aspirin had positive effect on pregnancy during implantation period.
Afsane Badrizadeh, Ali Farhadi, Mohamad Javad Tarrahi , Mandana Saki , Gholamreza Beiranvand ,
Volume 15, Issue 3 (9-2013)
Abstract
Background : Due to the harsh conditions of work and job problems of nurses, they experience more job stress and are more vulnerable. The nurses who have not suitable general mental health, are not able to render effective care to patients. Regarding the importance of mental health promotion of nurses and their key role in the quality of nursing care, this research was carried out to determine nurses mental health status.
Materials and Methods: This research was a correlated cross - sectional study conducted on 169 nurses working in hospitals of Lorestan university of medical sciences.Data gathered by a questionnaire including demographic information and mental health questionnaire (GHQ-28) and then using descriptive statistics (mean and standard deviation), inferential statistics (chi -squar) and T-test and ANOVA, and finally by use of SPSS software were analyzed.
Results: A total of 78 patients (46.2%) were asymptomatic and 91 (53. %) were marked. Overall total mental health was an average of 27.9% and a standard deviation of 13.1, respectively. Findings of the study showed no significant relation between demographic features (sex, marital status, record of service and income level) and mental health, but significant association was found between physical activity and mental health.
Conclusion: Regarding the significant and positive effects of physical activity on mental health, it seems necessary for nurses to do regular physical activities in their life and enhance their mental health.
Omid Ali Papi , Mohammad Saki , Hamid Mokhayeri , Ardeshir Sheikh Azadi , Ali Chegeni Sharafi , Mahmod Nabavi , Roshanak Namazi , Fatemeh Azimian,
Volume 15, Issue 4 (1-2014)
Abstract
Background: Hepatitis is a disease causing inflammation of the liver and impairment of its function .It is often transmitted through contaminated blood and blood products and may become chronic presenting with flu like symptoms .Also fatigue , loss of appetite , myalgia and arthralgia , nausea and vomiting are its remarkable symptoms. The aim of this research was to study the prevalence rate of hepatitis B in rural papulation of Garab, Padervand, Chaghabal and Tang-e Panj in terms of age, sex, job… and its comparison with prevalence rate in similar regions of our province and country. Materials and Methods: Aimed to determine the seroprevalence of HbsAg infection in areas of Garab, Padervand , Chaghabal and Tang-e Panj and relationship between defined epidemiological factors and the infection in the population under study, after providing a questionnaire containing the symptoms of the disease, the data were collected and blood specimens were obtained. Then the specimens were tested by ELISA . Results : Out of a total of 454 cases 227 were male and 227 were female ( identical sex ratio ) of them 27 cases (6.2 % ) were HBsAg positive . Out of infected persons 14 were male(51.9%) and 13 were female(48.1%) . Most infected ones were 20 to 40 years old and housewives , truck drivers and students were amongst the most infected cases . Conclusion : Based on the findings of the study heptitis B infection in these areas is far more frequent than the mean national rates amounting to 2 to 3 percent that is in accordance with surveillance system data in the mentioned areas . Although the findings does not define the main transmission pattern of the disease , when age and gender distribution of infected cases is considered ( almost equal sex ratio and preponderance of married ones ) we can state that this pattern is largely directed to sexual transmission .Although all age and sex groups are at risk , men and those at the age of 20 to 40 are more prone to infection . Occupation, blood transfusion , household dimension , vaccination history were significantly related to HbsAg infection .
Ghasem Saki , Sima Nasri, Maryam Jalali, Mohammad Reza Gholami ,
Volume 15, Issue 4 (1-2014)
Abstract
Background : Noise is a kind of environmental pollution affecting the life of humans. Many researches have been carried out on the effects of noise stress on the different parts of body, but few studies have been done on sexual systems. The aim of this study is to investigate the effects of noise stress on testosterone, LH and FSH.
Materials and Methods: Two groups of ten male rats have been introduced to 2 noisy environments of experimental and ordinary (with intensity of 90-120 decibel and frequency of 300-350 HZ) for fifty days from 7 am to 7 pm. After 50 days blood samples were collected from tail and level of testosterone, LH and FSH measured by Eliza and results were interpreted using T test with a significance of p<0.05.
Results: Statistical studies showed that the average of testosterone secretion, LH and FSH in comparison with control group, had a significant difference (p<0.05).
Conclusion: On the whole it can be said that sonic stresses decrease the level of testosterone, LH and FSH.
Mohamad Nabiuni, Homa Kouchesfahanii, Sakineh Azari, Bahram Delfan,
Volume 19, Issue 2 (10-2017)
Abstract
Background:Digestive system is the most common type of cancer in Iran with 38 percent of the cases.The risk of this cancer is influenced by both environmental and genetic factors. Curcumin is kind of phytochemicals which is important in chemoprevention strategy, in order to slow, block, or reverse the process of carcinogenesis.Researchhave shown that the possible role of curcumin to prevent or delay the diagnosis of colorectal cancer. In this research the effect of curcumin on proliferation of HT_29 cancerous cells were assayed.
Materials and Methods:In this experimental research HT_29 cell line were cultured in DMEM medium containing 10% FBS (Fetal Bovine Serum, Gibco, Invitrogen) and 100 U/ml penicillin and 100mg/ml streptomycin. Different concentrations of curcumin on the growth of HT_29 cells were determined by MTT assay and the type of death induced was assessed by DAPI staining method.All experiments were done three times and data were analyzed byone –way ANOVA test and Instate 3 software.
Results:The cell growth-inhibiting rate was about 53% at 50μM curcumin concentration after 24h of treatment(IC50). Vacuolation and significant decrease of cells were observed after 72h of treatment. Moreover, induction of apoptosis was observed with the DAPI staining method.
Conclusion:According to molecular mechanisms of cell proliferation and curcumin ability in the induction of pro_apoptotic proteins and the inhibition of anti_apoptotic proteins as well as inhibition of as survival pathways,like NF_KB and AKT, this predisposition makes curcumin a good anticancer drug.
Ehsane Rashidian, Sakineh Nadali, Seyed Mohammad Nayeb Aghaee , Hasan Noruzian,
Volume 19, Issue 5 (2-2018)
Abstract
Background: Most strains of E.coli with multi drug resistance are major cause of colibacillosis in poultry. The economic damages caused by E.coli infections, especially in the poultry industry and also the costs of the disease treatment with antibiotics are very high annually. Therefore, the aim of this study was to investigate the prevalence of bla CTX-M genes in E.coli isolates obtained from poultry disease in Khorramabad city.
Materials and Methods: In this present study, 100 E.coli isolates were collected in variable organs of birds with colibacillosis and then confirmed with biochemical tests. All the positive samples were there after investigated for the presence of CTX-M genes by PCR.
Results: 4 (%4) out of 100 E.coli isolates were ESBL positive based on the results of combined disk tests. PCR analysis using the specific primers revealed that %25 contained β-lactamases genes encoding CTX-M.
Conclusion: Giving the importance of E.coli infections in poultry and high prevalence of ESBL- producing strains of rapid diagnostics should used routinely to determine the strains in the laboratories. The results of this study show that the E.coli is saprophytic gastrointestinal reservoir for ESBL. This issue is very important in terms of public health and the transfer of antibiotic resistance to humans.
Rajab Rashidi, Atefeh Rokrok, Sakineh Mahdavi, Zahra Haghshenas, Mohammad Almasian,
Volume 20, Issue 1 (4-2018)
Abstract
Background: Based on recently conducted research, the reason for more than half of the absences from the work environment and one-third of the work-related compensation claims is attributable to musculoskeletal disorders. This study aimed to evaluate musculoskeletal disorders and assess the risk of these disorders among the welders of Khorramabad, Iran.
Materials and Methods: This descriptive-analytical study was conducted on 170 welders employed in Khorramabad, Iran. The welders were selected using the census sampling method. The prevalence of musculoskeletal disorders was evaluated using a Nordic questionnaire. To assess the risk of musculoskeletal disorders, the QEC method was used. Data analysis was done using the indices of central tendency and t-test.
Results: The results showed that the prevalence of the musculoskeletal disorders is highest in the back (70%), the knees (54.1%), the trunk (50%). The QEC assessment results showed that, in 83.8% of the cases, the risk of developing such diseases is high and very high.
Conclusion: This study showed that the prevalence of musculoskeletal disorders among the studied welders is high. Additionally, the risk of developing these disorders is also high. Based on these results, among the causes of musculoskeletal disorders among welders, uncomfortable working posture, manual lifting and carrying of loads, and the bending and twisting of the spine and back can be mentioned. In addition to these results, this study showed that the QEC method can offer reliable results.
Kourosh Amraei, Maryam Mokhtary Mosayebi, Kourosh Saki, Leila Fathi,
Volume 22, Issue 2 (8-2020)
Abstract
Background: Migraine headache is a common chronic clinical disorder. Psychological problems are high among these patients. This study examined the relationship between perfectionism dimensions and personality type with migraine severity of headache.
Materials and Methods: In this study a cross sectional method was used. Among patients referring to the neurologists in the city of Kerman 168 samples were selected. Participants responded to the personality type, intensity of headache and perfectionism dimensions' questionnaires, then data were analyzed using regression method.
Results: The results showed that there was significant correlation between type A personality and dimensions of perfectionism with migraine. Moreover, type A personality and community-oriented and self-oriented perfectionism are predictors of migraine, but other-oriented perfectionism cannot predict the migraine headache.
Conclusion: According to the findings of this research, personality characteristics, especially type A which are associated with a kind of pressure and urgency, moreover perfectionism of migraine patients should be considered in any treatment.
Afsaneh Badrizadeh, Hasan Rezaii Jamaloi, Mostafa Khanzadeh, Saeid Foroughi, Mandana Saki,
Volume 23, Issue 2 (5-2021)
Abstract
Background: One of the public health challenges in the worldwide is diabetes, and adherence to treatment is crucial. Adherence to treatment can help reduce the complications of the disease. Therefore, this study was performed to evaluate the status of adherence to treatment among patients with type 2 diabetes in Khorramabad.
Materials and Methods: In this cross-sectional study, 392 men and women with type 2 diabetes referred to comprehensive health centers in Khorramabad between May and August 2016 were studied. Demographic questionnaire and Morisky Medication Adherence Scale (MMAS-8) were used to collect data. Version 22 SPSS and descriptive analysis were used to analyze the data. Significance level in the present study was less than 0.05. Descriptive tests, Chi-square, Fisher's exact test, and independent t-test were used.
Results: The mean age of study participants was 56.03 ± 10.91. 68.9% (270 people) were women and 31/1% (122 people) were men. According to the score obtained from the Morisky questionnaire, a total of 219 patients (55/9%) followed the desired treatment and 173 (44/1%) followed the unfavorable treatment. There was a significant relationship between patients' adherence to treatment with the variables of gender, marital status, educational status, and their monthly income. No statistically significant between age and employment status with adherence to treatment were observed.
Conclusion: Findings of this study showed that adherence to treatment among patients with type 2 diabetes in Khorramabad is in a good level. Health policy makers should strive to ensure that all patients adhere to their treatment process with easy access to services and reduced costs.
Afsaneh Badrizadeh, Hasan Rezaii Jamaloi, Mostafa Khanzadeh, Saeid Foroughi, Mandana Saki,
Volume 23, Issue 3 (8-2021)
Abstract
Background: According to the growing prevalence of type 2 diabetes, the present study aimed to predict adherence to treatment based on social support variables and coping strategies to reduce the severity of this disease.
Materials and methods: In this cross-sectional study, 392 men and women with type 2 diabetes were evaluated using purposeful and convenient sampling. Wax social support and the Blings and Moss coping strategies questionnaire were used. Data were analyzed using SPSS software (version 22), descriptive statistics (frequency, percentage, and mean), and inferential statistics (Pearson correlation coefficient and regression analysis).
Results: The results indicated that the correlation between the subscales of social support and coping strategies with adherence to drug therapy was significant (P<.01). These measures could predict more than 27%) 27.1( of changes in compliance with drug treatment.
Conclusion: Social support and coping strategies can be two effective factors in promoting self-care behaviors and adherence to treatment in patients with diabetes. Including these strategies in educational, treatment, and care programs improves health and reduces long-term complications of the disease to increase the life expectancy of patients.
Bahram Kamarehie, Mohsen Saki Jafari, Ali Jafari, Mansour Ghaderpoori,
Volume 25, Issue 2 (8-2023)
Abstract
Background: Using baking soda and salt in preparing bread has different health effects on consumers. Therefore, this study aimed to determine the amount of baking soda, the percentage of salt, and the pH value in all kinds of bread produced in Khorramabad, Lorestan, Iran, in 2019.
Materials and Methods: This descriptive cross-sectional study was conducted in 2019 on bread consumed in Khorramabad during 12 months. The total number of samples was equal to 72 samples, including 24 Berber bread, 24 Sangak bread, and 24 lavash bread. The pH value, percentage of salt, and baking soda of baked samples, in each bread sample and in each season, was determined by standard method 2628.
Results: The max and min pH values were observed in Berber (6.47) and Sangak (5.10) breads, respectively. The max and min percentage of salt was observed in Berber and Sangak breads and lavash, respectively. In all the analyzed breads, on average, the min and max salt percentages were equal to 0.39 and 1.67, respectively.
Conclusion: Although the amount of baking soda in the preparation of bread has decreased compared to the last decade, the results of this study and other studies show that the unauthorized use of baking soda in the preparation of bread, especially Sangak and Berber, is still continuing in the country, especially in Khorramabad. Therefore, carrying out control and monitoring measures to manage this health problem should be considered in a consistent and continuous manner.
Amir Keyhani, Iraj Sharifi, Behroz Ezatpour, Fatemeh Sakifar, Hossein Mahmoudvand,
Volume 26, Issue 4 (10-2024)
Abstract
Background: This study aims to investigate the in vitro effects of ethanolic extract of Nectaroscordeum koelzii on the growth and induction of apoptosis in promastigotes of Leishmania tropica.
Materials and Methods: A growth inhibition test was conducted to evaluate the effects of the extracts and a control drug on human macrophage cell lines (THP-1) and promastigotes of the standard strain of Leishmania tropica (MHOM/IR/2002/Mash2), which was obtained from the Leishmaniasis Research Center of Kerman University of Medical Sciences. The MTT method (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) was used for this evaluation. Additionally, the activity of the caspase-3-like enzyme in promastigotes was assessed using colorimetric Caspase-3 activity assay kits (Sigma-Aldrich, Germany), following the manufacturer's instructions.
Results: The ethanolic extract of N. koelzii significantly reduced the viability of L. tropica promastigotes (P < 0.001), with an inhibitory concentration 50 (IC50) value of 88.7 μg/ml. The findings also indicated that the extract significantly increased the activation of the caspase-3 enzyme (P < 0.01). the cytotoxic concentration 50 (CC50) values for the ethanolic extract of N. koelzii and glucantime on THP-1 macrophage cells were 496.9 μg/ml and 1215.2 μg/ml, respectively.
Conclusion: The results of the present study indicate the potential anti-leishmanial effects of the ethanolic extract of N. koelzii on the promastigotes of Leishmania tropica. Induction of apoptosis may also be one of the most significant cellular mechanisms underlying the anti-parasitic effects of this extract. Additionally, the findings demonstrate that this extract exhibits low cytotoxicity towards normal human cells. However, further studies are needed to investigate the exact cellular mechanisms.
