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Showing 3 results for Exhaustive Exercise
Effects of Pomegranate peel hydroAlcoholic extract and vitamin E supplementation on Paraoxonase, myeloperoxidase Activities and nitric oxide levels following an exhaustive exercise in rats
Saeid Veiskarami, Mohamad Fathi, Hasan Ahmadvand, Ladan Rashidi, Reza Mohammad Rezaei Khorramabadi ,
Volume 18, Issue 4 (3-2017)
Abstract

Background: free radicals produced as a result of heavy training exercise especially oxygen species (ROS) damage to body tissues Which can be prevent from this by consuming antioxidant substances timely. The aim of this study was to evaluate effect of Pomegranate (Punica Granatum) peel hydro alcoholic on reduced of oxidative stress induced by an exhaustive exercise.

Materials and Methods: Thirty two weight-matched male Wistar rats were evenly divided into: 1) control: received saline (0.2 ml saline/ rat) by oral administration via epigastric tube. 2) Received oral administration of 200 mg/kg pomegranate peel hydro alcoholic extract (PPHE200). 3) Received oral administration of 250 mg/kg Pomegranate peel hydro alcoholic extract (PPHE250). 4) Received oral administration of vitamin E (vit E) 5 mg/kg. Animals were submitted to swimming exhaustive exercise stress for an 8-week. At the end of the experiment, blood samples were collected for serum. Serum samples were analyzed for paraoxonase-1(PON-1) and myeloperoxidase (MPO) activities and nitric oxide levels.

Results: Paraoxonase-1 (PON-1) activities serum were significantly increases in PPHE200 (23.03±1.47), PPHE250 (23.59±1.98) and vit E (25.38±2.65) than in the control (18.57±1.380) (p<0.05).In PPHE200 (32.76±9.97) ،PPHE250 (31.45±6.05) and vit E (24.94±4.65) treated animals was determined in serum where myeloperoxidase activities reduced significantly compared with control (40.70±6.14) (p<0.05). Levels of Nitric oxide levels were significantly lower in PPHE 200 (46.59±2.48), PPHE250 (40.27±2.62) and vit E (36.25±3.82) treated than in control (47.18±5.36) (p<0.05).

Conclusion: Results indicated that Pomegranate peel hydro alcoholic extract supplementations can strength antioxidant defense system and anti-inflammatory induced by exhaustive exercise.


The effects of Short-Term aqueous Saffron extracts consumption on malondialdehyde and anti-oxidant system content of liver of young male rats following an acute bout of exhaustive exercise
Amir Khosravi, Omid Ali Omidali, Bahram Rasoulian, Seiros Choobineh,
Volume 19, Issue 1 (6-2017)
Abstract

Background : Despite regular exercise benefits, acute exhaustive exercise elicits oxidative damage in liver. The present study aims to investigate the effects of a week aqueous Saffron extracts consumption on malondialdehyde (MDA) and superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPx) Antioxidant enzymes alterations content of liver of young male rats following an acute bout of exhaustive exercise.

Materials and Methods: We randomly classified 48 Wistar male rats were assigned into following three groups 16 rats per group: 1) control 1 (saffron extract solvent); 2) control 2 (saffron extract solvent+ training); 3) experimental (aqueous saffron extract, 50 mg/kg + training).After a week, half of each group were killed without exhaustive, but the remaining rats (control 2 and experimental) were killed immediately after performed an acute bout of exhaustive exercise and SOD, CAT , GPx and MDA in their liver were measured.

Results: The MDA level and anti-oxidant enzymes activities didn’t change significantly, in the liver tissue in experimental group unlike control group of rats following an acute bout of exhaustive exercise

Conclusion: The consumption aqueous extract of saffron stigma in rats leads to the reinforcemen of the antioxidant defense system and prevented the MDA level and anti-oxidant enzymes defense system in the liver tissue of rats following an acute bout of exhaustive exercise.


Effect of 12 weeks of green tea extract consumption on total antioxidant capacity (TAC), malondialdehyde (MDA) levels and superoxide dismutase, glutathione peroxidase and catalase activity of old rats' heart tissue in response to a bout acute exhaustive exercise
Ahmad Kazemi, Nasser Behpour, Ahmad Hematfar,
Volume 22, Issue 2 (8-2020)
Abstract
Background: The incidence of heart disease increase with age. Green tea is an antioxidant which can prevent cellular aging. Therefore, the present study aims to investigate the effect of 12 weeks of green tea extract consumption on total antioxidant capacity (TAC), malondialdehyde (MDA) levels and superoxide dismutase, glutathione peroxidase and catalase activity of old rats' heart tissue in response to acute exhaustive exercise.
Materials and Methods: 32 male rats were randomly categorized into two groups of supplement and non-supplement each consisting of 16 rats. The supplement group received green tea extract for 12 weeks. At the end of the 12 weeks, each of these groups was further divided into two groups of rest and acute exhaustive exercise. The non-supplement with the rest group was called control group. The non-supplement with exercise group was called exercise group. Further, the supplement group with the rest was called supplement group and finally the last group was entitled supplement with exercise. After 12 weeks of taking green tea extract, one session of acute exhaustive exercise was held on the treadmill. Sandwich ELISA method was used to measure TAC and MDA content and superoxide dismutase, glutathione peroxidase and catalase activity
Results: The results showed that 12 weeks of green tea extract consumption increased TAC and decreased MDA levels. Furthermore, increased superoxide dismutase, glutathione peroxidase and catalase activity in response to a bout acute exhaustive exercise.
Conclusion: According to the results of this study, 12 weeks of green tea extract consumption can increase TAC levels and increase the activity of antioxidant enzymes at rest and after acute exhaustive exercise.

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