Showing 18 results for Treatment
Shahla Enshaieh , Hamid Rashnoo , Amir Hosein Siadat , Ali Sadeghinia ,
Volume 8, Issue 3 (11-2006)
Abstract
Background: Telogen effluvium is a self-limited, non-scarring disease that shows itself as a diffuse hair loss of the scalp that usually occurs 3 months after an acute illness. Theoretically, Minoxidil solution has been suggested as a treatment for this condition. In this study, we compared the efficacy of the minoxidil and an herbal drug containing urtica diocia, chamomilla, thymus vulgaris, equisetum avenues and foeniculum vulgare for treating telogen effluvium.
Material and methods: This study was a double – blind prospective study. 24 patients with telogen effluvium were allocated randomly in two groups and were treated with minoxidil and the herbal drug. Data were analyzed statistically.
Results: The mean duration of telogen effluvium in the minoxidil group was 17 weeks and in the herbal drug group was 7 weeks. This difference was statistically significant.
Conclusion: From this study, it is condoled that this herbal drug is effective in telogen effluvium although more studies are recommended in this field.
Hedayat Nazari , Mandana Saki , Parisa Sohrabi , Mohammad Javad Tarrahi , Mohammad Movahedi , Afsaneh Badrizadeh , Kheirollah Baqeri ,
Volume 9, Issue 3 (10-2007)
Abstract
Nazari H1, Saki M2, Sohrabi P3, Tarrahi MJ4, Movahedi M5, Badrizadeh A6, Baqeri Kh7
1. Assistant Professor, Department of Psychiatry, Faculty of Medicine, Lorestan University of Medical Sciences
2. Instructor, Department of Psychiatry, Faculty of Nursing and Midwifery, Lorestan University of Medical Sciences
3. General Practitioner, Neurology and Psychoiatry Hospital, Khorramabad
4. Instructor, Department of Epidemiology and Statistics, Faculty of Medicine, Lorestan University of Medical Sciences
5. Assistant Professor, Department of Epidemiology, Faculty of Medicine, Lorestan University of Medical Sciences
6. B.Sc of Nursing, Staff Member of Research and Technology Office, Lorestan University of Medical Sciences
7. B.Sc of Nursing, Psychology hospital
Abstract
Background: Major depressive disorder (MDD) is one of the most common mental disorders all over the world. An effective treatment preserves an acceptable level of function in the affected patients. Different drugs are used in the treatment of MDD, and each of them has specific therapeutic and adverse effects. Recently, SSRI drugs are used in the treatment of this disorder, and yet there is not enough study about them. Thus, we decided to compare the effectiveness and adverse effects of Nortriptyline with that of Citalopram in MDD.
Materials and methods: In this double-blinded clinical trial, 80 MMD (DSM-IV-TR) patients, who that not any other mental, substance and organic disorders were selected. Samples were randomly assigned into two groups which were treated with Nortriptyline or Citalopram. Efficacy and adverse effects were evaluated at 2, 4, 6, 8 and 12 weeks after the treatment. Data were analyzed by SPSS software.
Results: Efficacy was similar in two groups, and no significant differences between the two groups were observed in the mean scores. The comparison of adverse effects between the two groups showed a significant difference in the hypersomnia, dry mouth, anorexia and nausea. There was not a significant difference between the two groups in the sexual dysfunction, insomnia headache, tremor, vertigo, obesity, diarrhea, vomiting and abdominal pain.
Conclusion: Tricycles and SSRI drugs have an equal efficacy in the treatment of MDD. But they have different adverse effect profiles, thus they must be administrated with an attention to their adverse effects.
Viktoria Beigi Boroujeni , Ali Akbar Beigi , Majid Avijgan , Nasim Beigi Boroujeni , Hojatollah Roohi Boroujeni , Fatemeh Deris ,
Volume 11, Issue 1 (4-2009)
Abstract
Babak Mirzashahi, Mahdiye Ahmadifar, Mehdi Birjandi, Yadollah Pournia,
Volume 13, Issue 2 (8-2011)
Abstract
Hallux valgus or laterally deviation of thebig toe to the out side is a complex disease. If there is not any treatment it will cause deviation of other toes. Hallux valgus is 3 times more common in females that may cause uncomfortable deformity of foot , problem with wearing unsuitable and narrow-toed box shoes and pain on the inside of the big toe over the metatarsal joint , therefore patients may refer to physician. Untreated Hallux valgus may cause hamer toe deformity of the second toe.
Materials and Methods: This study was a cohort study carried out on the patients referred to orthopedic clinic of Ashayer hospital with complaint of Hallux valgus. Two groups of 30cases were ramdomly selected and then the splints designed by us were given to case group and Night splint and interdigital pad were given to the control group. The patients were followed for one year as every three months and in every time weight bearing antroposterior radiography of both foot were taken and Hallux valgus and inter metatarsal angles were measured, and data were analyzed using SPSS and repeated measure test.
Results: In the patients who used our splints regularly Hallux valgus angles decresed more considerably than those who used splints available on the market ( p<0.001).
Conclusion: This study showed that despite the contraversies in nonoperative treatment of Hallux valgus, if the Hallux valgus angle of patients are mild to moderate, this splints can be used to treat it.
Dr Seyed Abas Tabatabai, Dr Seyed Mozafar Hashemi, Dr Mojtaba Ahmadi Nejad , Aram Toolabi , Dr Sadi Afshar Pour ,
Volume 13, Issue 2 (8-2011)
Abstract
Chest wall masses are a broad spectrum of bening or malignant growth of cells.Different studies reported different results about chest wall damage,but there is not holistic information about different types of thoracic damage in patients yet.The aim of this research is to study frequency of operated chest wall tumors in Isfahan Al Zahra hospital based on epidemiologic variables, how to respond to the treatment and the fate of these Patients.
Materials and Methods: This descriptive cross-sectional study was conducted in Al Zahra training and treatment center in 2009. The sampling method was census. The records of all patients who underwent surgery from 2007 to 2009 were studied. The data were collected by a special questionnaire and analyzed by SPSS software. The Chi-square and T-student tests were used for data analysis.
Results: 112 records of the patients with chest wall tumors were studied that 46 cases(41.1%) were benign and 66 cases(58.2%) were malignant. The frequency distributions of malignant tumors in males and females were 56.5% and 62% and the difference between two sexes was not statistically significant (P= 0.55).
Conclusion: According to the results of this study about 59% of the chest wall tumors were malignant and in the case of being hesitant about existing a mass on the chest wall, needed measurements for treatmentand and on time removal of the mass must be done.
Dr Abolreza Kheirollahi , Dr Farhad Shahsavar, Tomaj Sabooteh ,
Volume 13, Issue 2 (8-2011)
Abstract
Immunoinfertility because of antisperm antibody (ASA) is one of the important causes of infertility in humans. The incidence of ASA in infertile couples is 9-36% depending on the reporting center. The prevalence of ASA is 8-21% in the infertile male partners and 6-23% in the infertile female partners.
There are several methods to detect ASA. In the past, the clinical interest in ASA was hampered by the fact that a standardized assay for the detection of ASA was lacking. However, it has to be clarified whether each antibody binding to an antigen, which is identified on the sperm surface, also influences sperm function.
Several methods have been reported for treatment of immunoinfertility. Most of the available techniques have side effects, are invasive and expensive, have low efficacy, or provide conflicting results.This review article will help to increase our knowledge about diagnosis and treatment methods of ASA.
Hossein Masoumbeigi, Abbas Rezaee , Hatam Godini ,
Volume 14, Issue 4 (12-2012)
Abstract
Background : Pseudomonus stutzeri bactrerium is one of the most important and effective denitrifier bacteria in wastewater. With regard to the importance of effects of nitrate on water resources and human health and role of metronidazole inhibition, this study was done with the aim of survey of effect of metronidazole different concentrations on biological denitrification of Pesudomonas stutzeri in wastwater.
Materials and Methods: This research was an experimental study. After sampling from raw wastewater, identification and isolation of pseudomonus stutzeri bactrerium were done. Bacteria suspension in specific culture medium and metronidazole different concentrations in deionized water and nitrate different concentrations for experimentals of nitrate removal under anoxic conditions was prepared and metronidazole inhibition experiments on activity of denitrification by pseudomonus stutzeri in synthetic and real wastewater were conducted.
Results: Metronidazole at concentrations of 100, 200, 300 and 400mg/l, in synthetic wastewater containing nitrate concentrations to 500mg/l, had no inhibitory effect on activity of denitrification by pseudomonus stutzeri. Metronidazole at concentrations of higher than 800mg/l in synthetic wastewater and higher than 500mg/l in domestic wastewater had inhibitory effect. In 800mg/l metronidazole concentrations, with increasing the concentration of substrate(nitrate), significant reduction in the rate of nitrate removal by pseudomonus stutzeri was observed. This bacterium was added to three samples of domestic sewage, but had no effect on the rate of nitrate removal.
Conclusion: With ergard to strong ability of Pseudomonus stutzeri to remove nitrate high concentrations and high resistance of this bacterium against metrinidazole, biological denitrification process can have a high potential to be used for removal of nitrates high concentrations from industrial wastewater, particularly pharmaceutical industries wastewater.
Kamal Solati Dehkordi , Masoud Nikfarjam,
Volume 15, Issue 3 (9-2013)
Abstract
Background: Depression is one of the common our age psychiatry disorders. The purpose of the present study to determine the effect of family psychoeducation and standard treatment medical on improvement and prevent relapse symptoms of major depression patients.
Materials and Methods: This is a clinical trial using convenience sampling method to randomly recruit 60 patients admitted with major depression disorder and were randomly allocated into two equal groups. Two groups received standard treatment medical that one of the groups in eight under went family psychoeducation sessions. Beck Depression Inventory II was applied to all two groups befor and after and follow –up stages .Data analyzed by covariance (Ancova)test.
Results: our findings indicated there were significant difference between Experimental group and control group after therapeutic interventions and follow-up stages (P<0.05).
Conclusion: Standard treatment medical in addition to by family psychoeducation in major depression disorder patients can more efficient in improving and prevent relapse depression of symptoms in compared to standard treatment medical.
Samneh Khademikia, Ali Haghizadeh, Hatam Godini, Ghodratolah Shams Khorramabadi,
Volume 18, Issue 3 (12-2016)
Abstract
Background: In the last two decades the using of artificial intelligence models for correct operation of the water treatment plant and maintain the stability of systems in favorable conditions, much researches has been done in this area. These models to simulate the behavior of water treatment systems can be used as an effective tool and to be used in the prediction of plant performance. The aim of this study was to evaluate of Khorramabad wastewater treatment plant performance (WWTP) using artificial intelligence network (AIN).
Materials and Methods: In this study, by using the AIN-LM and underlying the quality parameters measured at the entrance of plant (T, PH, DO, BOD, COD, TSS, TDS, NO3, PO4), the corresponding three parameters BOD, COD and TSS in the output of wastewater treatment plant was predicted. Statistical indicators used in this study were R, MSE and the software Matlab and SPSS (test T-test), respectively.
Results: Based on the results, BOD, COD and TSS, respectively, with a maximum R, 0/98, 0/91 and 0/92 for the train data and 0/5, 0/66 and 0/5 for the test data and minimum MSE, 3/5, 33/15 and 2/17 for the train data 11, 115 and 20/99 were predicted for the test data, and the results were acceptable. Also, by calculating the percent removal of pollutants in the output of plant was revealed that TSS had the maximum efficiency of pollutant removal in wastewater treatment plant and was equal to 87/68 %. Also, other amounts of pollutant were closed to TSS.
Conclusion: In this study, AIN-LM created a reliable tool for predicting the performance of Khorramabad wastewater treatment plant and could predict the quality of effluent on the basis of measured parameters. So, remove of pollutants through the results were obtained by using the AIN-LM network, showed that, it was a good model, so the observed data indicates that confirm of the performance this model, as well. Also, the reduction of qualitative values as standard values recommended by the DOE indicates that the relatively good performance of the WWTP.
Masomeh Movahedi, Mohamad Ebadi Rad , Kolsom Kariminejad, Fayezeh Moravej,
Volume 19, Issue 2 (10-2017)
Abstract
Background: The researches of recent two decades are representative of the importance and special attention of various countries to the procrastination issue. This research carried out with the aim of the investigation of the effectiveness of cognitive behavioral and behavior management therapies on procrastination in students of the Lorestan University of Medical sciences.
Materials and Methods: The experimental study method was used in this study that the design of pretest- posttest with experimental and control groups were used. Among the all of the male and female students in academic year of 2014, 393 subjects were selected as a sample of study using the convenient sampling method. At first the Tuckman' procrastination questionnaire were completed by 393 students and among them 76 subjects that diagnosed with procrastination were selected and assigned to experimental and control groups.
Result: The findings of this research indicated that the amount of the prevalence of procrastination in all students was 19/33%. 29/41% of the male population under study had procrastination, but this amount for females were 14/96%. Also the results represented the effectiveness of two therapies of cognitive behavioral and behavior management on reduction of procrastination. Furthermore, there were significant differences between the gender and the type of the treatment.
Conclusion: According to the results of this study, it seems that the procrastination is from the impressible cognitive constructs and regarding this issue, these two treatments by emphasis on cognitive constructs could decrease the amount of the procrastination on experimental groups. Also the differences between the treatment methods among male and female, is representative of differences of cognitive constructs corresponding to the gender that seems not to be irrelevant to gender roles.
Fatemeh Jafari Pour , Tahereh Toulabi, Halimeh Khaton Zare Elmi , Sabah Khoshnoud, Somayeh Riahi, Hadis Koganinejad ,
Volume 19, Issue 3 (10-2017)
Abstract
Background: Ebola Virus Disease (EVD) has been known as a hemorrhagic fever, a severe and often fatal illness among humans.
Materials and Methods: This virus is transmitted through contact with the blood or body fluids of an infected person, infected objects such as needles, infected animals or bush meat. The history of mortality was more than 80 percent, but modern medical and public health had been able to reduce this figure and the impact of Ebola on individuals and communities.
Results: Currently there is no standard treatment for Ebola, so preventing infection and preventing further spread of the virus is important. Since the mortality rate is high and there is no specific treatment for it and it is also possible to use it as a biological weapon in wars. Therefore, a review of epidemiology, clinical and laboratory symptoms and management of this disease is needed as a first step for accurate diagnosis and timely response.
Conclosion: In this regard, the present review article was conducted using the keywords of Ebola Virus, Epidemiology, Diagnosis, Treatment, Prevention and Bioterrorism in Pubmed, Elsevier, Google Scholar, SID, Google and other websites.
Ahmad Mohammadi Moghaddam, Vahid Tadibi, Naser Behpoor, Afshin Nazari,
Volume 21, Issue 2 (9-2019)
Abstract
Background: Physical activity and sport act as a non-drug treatment and prevention of non-contagious diseases. Accordingly, one of the most widely used tools is endurance training. The aim of this study was to survey the pre-treatment effects of continuous and intermittent endurance training on the gene expression of osteopontin in the heart tissue of male wistar rats following the induction of myocardial infarction.
Materials and Methods: In the present study, 32 rats were kept under standard conditions and divided into four groups (healthy control group, ischemic control group, continuous training group and intermittent training group). The healthy control group did not undergo myocardial infarction, while the ischemic control group underwent induced myocardial infarction after eight weeks. The training groups also did endurance training on treadmills for eight weeks and were subjected to induced myocardial infarction after 48 hours of rest. One week after confirmed occurrence of ischemia, the rats’ hearts were isolated and qRT-PCR was used to measure OPN gene expression.
Results: The results of this research showed that OPN gene expression in the heart tissue of male wistar rats increased significantly after the induction of myocardial infarction compared to the healthy control group (p<0/05). Also, the relative expression of this gene in the ischemia control group was significantly higher than both the two training groups (p<0/05). Comparing the two types of training, the relative level of OPN expression in the group that underwent continuous training was lower (p<0/05).
Conclusion: Cardiac infarction leads to an increase in cardiovascular risk factors and cardiac fibrosis. Endurance training, especially regular continuous training, can moderate the increase in these factors.
Amir Shakarami, Seyedeh Fatemeh Mousavi, Mehran Naghi Beiranvand, Hossein Poor Esmaeil,
Volume 22, Issue 3 (11-2020)
Abstract
Background: No proven effective treatment for coronavirus disease (COVID-19) currently exist. Different drugs have different effects on patients with Covid-19, and the potential benefits or harms of the proposed drugs for the treatment of this disease need to be discussed more fully. The aim of this study was to systematically review the effectiveness of the proposed drugs in the treatment of patients with Covid-19.
The present study is a systematic review that used SID, PubMed, Web Science, EMBASE, Scopus, and Science direct, Google Scholar, JAMA, WHO and CDC databases to access related articles. In order to search for articles, only English articles with the keywords Covid19, treatment, Remdesivir, Hydroxychloroquine, Ritonavir, Tocilizumab and all possible combinations of these words during 2019 and 2020 were examined. Out of 250 papers obtained, 20 papers had initial conditions and finally 9 clinical trial papers related to Covid-19 treatments were reviewed.
Initial studies on chloroquine and hydroxychloroquine (with and without macrolides) were found to be effective in the treatment of Covid-19 patients, but further studies have shown that these drugs do not have a positive effect on Covid-19. Also, the use of chloroquine and hydroxychloroquine in patients led to an increase in their mortality. There were different results for lopinavir and ritonavir, some of which showed improvement in symptoms and in others exacerbation of symptoms and complications. Remdesivir causes side effects such as nausea, constipation, hypokalemia, hypotension and elevated liver enzymes.
Chloroquine and Hydroxychloroquine have no effect on the recovery of patients with Covid-19. The positive or negative effect of lopinavir / ritonavir requires clinical trials and research. Remdesivir improves patients with Covid-19. It is recommended that caregivers and medical and nursing staff closely monitor patients receiving remdesivir for drug side effects.
Zahra Mobasher, Nasrin Bagheri, Mohammad Abasi, Zahra Tanha,
Volume 23, Issue 0 (11-2021)
Abstract
Background: Introduction Heart disease and its psychological complications are known to be the most important causes of mortality in the world. Compares in heart patients.
Materials and Methods: The present study was a pre-test, post-test with a control group. The statistical population included a number of women with heart disease in Khorramabad in 1399, of whom 45 were available ( 15 people in the first group 15 people in the second group 15 people in the control group) Intervention in the two treatment groups was held separately in 10 sessions of 90 minutes each and no training was applied for the control group. The instrument of this study was the 12-item self-care scale developed by Jarsma and the 20-item treatment follow-up (5 general follow-up questions and 15 specific follow-up questions) developed by Hayes. The test answered its questions and multivariate analysis of covariance was used to analyze the data.
Results: The combination of acceptance and commitment-based therapy and self-compassion training and emotion-oriented cognitive-behavioral therapy improves self-care and adherence to treatment in women with cardiovascular disease (p <0.05) and percentage Their improvement was higher than the control group (p <0.05). But the two experimental groups were not significantly different (P <0.05).
Conclusion: The combination of acceptance and commitment-based therapy and self-compassion training and emotion-oriented cognitive-behavioral therapy leads to continuity and management in self-care, symptom detection and adherence to physician recommendations in women with cardiovascular disease.
Leila Noorazar, Mahshid Mehdizadeh, Behrouz Farhadi Hosseinabadi, Sayeh Parkhideh, Abbas Hajifathali,
Volume 23, Issue 0 (11-2021)
Abstract
Background: Acute myeloblastic leukemia (AML) is one of the most common types of blood malignancies and has a high mortality rate in the world. Cytogenetic abnormalities are one of the several risk factors that have been suggested for this disease. With advances in the design and use of various drugs for AML treatment, leukemic cells using various mechanisms can become resistant to the cytotoxicity of drugs. Indeed, these factors result in cancer survival and treatment failure. On the other hand, predicting prognosis and relapse of the disease depends on drug resistance of leukemic cells and choosing of treatment process. Our aim in this review article is to investigate the most common ways of AML treatment failure. By knowing these factors, more effective drugs are produced and new therapeutic protocoles are used in the treatment of AML.
Arash Amin, Morteza Amraei, Nasrollah Moradifar,
Volume 23, Issue 0 (11-2021)
Abstract
Background: It is not long before the outbreak of coronavirus disease (COVID-19) and its transformation into a pandemic. Over the course of late December 2019, studies have shown that cardiovascular comorbidities are more common in patients with COVID-19 and that these patients are at higher risk for complications and mortality; however, it is not yet clear whether underlying cardiovascular diseases pose a separate risk or whether they are associated with other factors, such as age and sex. The purpose of this study is to review the underlying cardiovascular diseases during the COVID-19. For this purpose, the main review articles using keywords such as “COVID-19”, ‘Coronavirus”, “SARS-CoV-2”, “Cardiovascular diseases”, “Myocarditis”, “Acute coronary syndromes”, “Heart failure”, and “Ischemic heart disease: were collected from PubMed, Scopus, Google Scholar, Web of Science and other reputable databases. The results showed that myocardial injury was present in more than 25% of critical cases and appeared in two patterns: acute myocardial injury and dysfunction during the presentation and myocardial injury caused by exacerbation of the disease. Continuation of angiotensin converting enzyme inhibitors and angiotensin receptor inhibitors is recommended based on the evidence at this time. A number of promising therapies are under consideration, but none have been clinically proven to be effective to date. The present study indicates that during the corona pandemic, more attention should be paid to people with cardiovascular disease and effective treatments should be used for them based on new studies.
Afsaneh Badrizadeh, Hasan Rezaii Jamaloi, Mostafa Khanzadeh, Saeid Foroughi, Mandana Saki,
Volume 23, Issue 2 (5-2021)
Abstract
Background: One of the public health challenges in the worldwide is diabetes, and adherence to treatment is crucial. Adherence to treatment can help reduce the complications of the disease. Therefore, this study was performed to evaluate the status of adherence to treatment among patients with type 2 diabetes in Khorramabad.
Materials and Methods: In this cross-sectional study, 392 men and women with type 2 diabetes referred to comprehensive health centers in Khorramabad between May and August 2016 were studied. Demographic questionnaire and Morisky Medication Adherence Scale (MMAS-8) were used to collect data. Version 22 SPSS and descriptive analysis were used to analyze the data. Significance level in the present study was less than 0.05. Descriptive tests, Chi-square, Fisher's exact test, and independent t-test were used.
Results: The mean age of study participants was 56.03 ± 10.91. 68.9% (270 people) were women and 31/1% (122 people) were men. According to the score obtained from the Morisky questionnaire, a total of 219 patients (55/9%) followed the desired treatment and 173 (44/1%) followed the unfavorable treatment. There was a significant relationship between patients' adherence to treatment with the variables of gender, marital status, educational status, and their monthly income. No statistically significant between age and employment status with adherence to treatment were observed.
Conclusion: Findings of this study showed that adherence to treatment among patients with type 2 diabetes in Khorramabad is in a good level. Health policy makers should strive to ensure that all patients adhere to their treatment process with easy access to services and reduced costs.
Amir Keyhani, Iraj Sharifi, Behroz Ezatpour, Fatemeh Sakifar, Hossein Mahmoudvand,
Volume 26, Issue 4 (10-2024)
Abstract
Background: This study aims to investigate the in vitro effects of ethanolic extract of Nectaroscordeum koelzii on the growth and induction of apoptosis in promastigotes of Leishmania tropica.
Materials and Methods: A growth inhibition test was conducted to evaluate the effects of the extracts and a control drug on human macrophage cell lines (THP-1) and promastigotes of the standard strain of Leishmania tropica (MHOM/IR/2002/Mash2), which was obtained from the Leishmaniasis Research Center of Kerman University of Medical Sciences. The MTT method (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) was used for this evaluation. Additionally, the activity of the caspase-3-like enzyme in promastigotes was assessed using colorimetric Caspase-3 activity assay kits (Sigma-Aldrich, Germany), following the manufacturer's instructions.
Results: The ethanolic extract of N. koelzii significantly reduced the viability of L. tropica promastigotes (P < 0.001), with an inhibitory concentration 50 (IC50) value of 88.7 μg/ml. The findings also indicated that the extract significantly increased the activation of the caspase-3 enzyme (P < 0.01). the cytotoxic concentration 50 (CC50) values for the ethanolic extract of N. koelzii and glucantime on THP-1 macrophage cells were 496.9 μg/ml and 1215.2 μg/ml, respectively.
Conclusion: The results of the present study indicate the potential anti-leishmanial effects of the ethanolic extract of N. koelzii on the promastigotes of Leishmania tropica. Induction of apoptosis may also be one of the most significant cellular mechanisms underlying the anti-parasitic effects of this extract. Additionally, the findings demonstrate that this extract exhibits low cytotoxicity towards normal human cells. However, further studies are needed to investigate the exact cellular mechanisms.
