Mohammad Reza Bigdeli , Ali Akbar Maratan ,
Volume 10, Issue 4 (3-2009)
Abstract
Introduction: Ischemic preconditioning (IPC) is an endogenous phenomenon that can induce ischemic tolerance (IT) in variety of organs such as brain. In this study, we examined the intermittent and prolonged dose of normobaric hyperoxia (HO) on neurologic deficit scores, infarct volume, and catalase activity. Material and Method: The rats were divided to four main groups. First two main groups were exposed with HO in prolonged (24h PrHO) and intermittent (4h×6days InHO) groups and second two main group acted as controls, and were exposed to 21% oxygen in the same chamber (room air, RA) continuously (24h PrRA) and discontinuously (4h×6days InRA). Each group subdivided to three subgroups. After 24 h, first subgroup were subjected to 60 minutes MCAO followed by 24h of reperfusion. Then, IT induced by InHO and PrHO were measured by neurologic deficit scores and infarct volume. Second and third subgroups were called sham-operated and intact subgroups for assessment of the effect of HO on catalase activity. Result: Our findings indicate that InHO and PrHO are involved in the induction of IT. Pretreatment with InHO and PrHO reduced neurologic deficit scores and infarct volume significantly. InHO and PrHO increase catalase activity significantly. The catalase activity of prolonged HO groups significantly was more than that of intermittent HO groups. Conclusion: Although further studies are needed to clarify the mechanisms of ischemic tolerance, InHO and PrHO seem to partly exert their effects via increase catalase activity.
Hamid Momeni , Ashraf Salehi , Abaolfazl Seraji , Saeed Foruoghi ,
Volume 11, Issue 4 (2-2010)
Abstract
One of disorder with destroyed of function and perception of body’s structure is cerebrovascular accident (CVA). By current statistical results, CVA is the third agents of death. Self care is the one section of rehabilitation in patients with CVA. By nurse’s support, the patient will performance self care and he will acquire feeling self- respect. Materials and Methods: This quasi experimental research was carried out on 42 CVA patients. Data collection instrument was SS- QOL questionnaire. First QOL indicator was measured by SS- QOL questionnaire. In experimental group self care program was instructed. After 5 weeks, patient’s QOL in two groups were measured again by the same questionnaire. T test, Chi Square and Willcaxon test was used to data analysis. Results: A significant difference was observed between QOL score before and after self care program in experimental group (p≥0.001), as well as a significant difference was seen between QOL score in experimental and control groups (p≥0.00128). Conclusion: Findings of this research showed that education of self care to patients by nurses in hospital or home can increase quality of life in the patients with CVA.
Arezo Homam Zakere Langerode, Ghasem Nazere, Masood Mohamade, Azam Davoode,
Volume 23, Issue 0 (11-2021)
Abstract
Background: Stroke is the most important cause of death in the world and in Iran after heart disease and cancer. The aim of this study was to determine the effectiveness of neuropsychological rehabilitation on memory and executive function in patients with stroke in Yasuj.
Materials and Methods: The method of this research was quasi-experimental with pretest-posttest design with control group and 6-month follow-up. The statistical population of the study consisted of all patients with stroke who referred to Shahid Beheshi Hospital in Yasouj. From the statistical population, 30 people were selected by purposive sampling method and then randomly assigned to two experimental groups (15 people) and control (15 people). The experimental group for 22 sessions of 90 minutes under the method Underwent neuropsychological rehabilitation therapy. In order to collect research data, the Concise Examination Scale, Wechsler Working Memory Test, Adult Wechsler Clinical Memory and the Tower of London Problem Solving Test (were used. Data were analyzed by analysis of covariance or repeated measures with Bonferroni post hoc test.
Results: The results of analysis of covariance showed that the neuropsychological rehabilitation approach was effective on memory and executive function of people with stroke and significantly improved memory and executive function of people with stroke (P < 0/05).
Conclusion: According to a research finding, the neuropsychological approach to improving memory can be the executive function of people with stroke.
