Volume 16, Number 4 (2-2015)                   yafte 2015, 16(4): 70-78 | Back to browse issues page


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Hosseini S, Shojaei S, Hosseini S. The effects of cinnamon on glycemic indexes and insulin resistance in adult male diabetic rats with streptozotocin. yafte. 2015; 16 (4) :70-78
URL: http://yafte.lums.ac.ir/article-1-1795-en.html

Associate Professor, Department of Biology Science and Research Branch, Islamic Azad University,Shiraz Branch,Shiraz, Iran
Abstract:   (2455 Views)
Background: Diabetes is a common disease that for its treatment and control different methods are recommended such as the use of natural remedies and lifestyle modification. Since the use of herbal medicines have less side effects than many chemical drugs, hence, this study aimed to investigate the effect of cinnamon extract on blood glucose, insulin and insulin resistance in diabetic rats with streptozotocin. Materials and Methods: This experimental study was conducted on 40 adult male rats, that were randomly divided into 4 groups including non diabetic control, diabetic control and two experimental groups receiving doses 60mg/kg of cinnamon extract for 3 and 6 weeks. At the end, by phlebotomizing of rats' heart, blood glucose and insulin were measured and using HOMA score insulin resistance was measured. To be normal data distribution, Kolmogorov-Smirnov test was done and data analyzed by SPSS-20 software and ANOVA and post hoc Tukey tests. Results: The results showed that in the group receiving the cinnamon extract, glycemic and insulin indexes were significantly adjusted. Conclusion: Cinnamon is probably due to have flavonoid and antioxidant compounds with antioxidant by increasing glucose uptake via the different body cells and due to reduction of oxidative stress level led to adjust glycemic and insulin indexes of blood
Full-Text [PDF 189 kb]   (937 Downloads)    
Type of Study: Research |
Received: 2015/02/10 | Accepted: 2015/02/10 | Published: 2015/02/10

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