Volume 22, Issue 3 (11-2020)                   yafte 2020, 22(3): 48-57 | Back to browse issues page

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Ghafarzadeh M, Janani F, Yari F. Evaluation of the relationship between maternal serum vitamin D level with premature amniotic sac rupture in pregnant women referred to Asalian Hospital in Khorramabad 2019-2020. yafte 2020; 22 (3) :48-57
URL: http://yafte.lums.ac.ir/article-1-3080-en.html
Lorestan University of Medical Sciences, Khorramabad, Iran
Abstract:   (2310 Views)
Background: Vitamin D deficiency is common during pregnancy and childbirth. Recent findings suggest that vitamin D deficiency is associated with adverse pregnancy outcomes. This study was performed to determine the association between low levels of maternal serum vitamin D and some adverse pregnancy outcomes such as premature rupture of embryonic membranes.
Materials and Methods: 73 pregnant women with premature rupture of embryonic membranes as a case group 73 healthy pregnant women as control group were randomly selected from 18 to 35 pregnant women with a gestational age of 28 to 41, who had been referred to Asalian Hospital within 6 months, were selected. Blood levels of vitamin D were measured in both groups. Demographic information as well as data from laboratory results and patient histories were collected using a researcher checklist. Finally, patients were statistically evaluated for vitamin D levels and study factors.
Results: The mean vitamin D level in patients with PROM was 22.49 7 ±7.25nm/lit and the mean vitamin D level in patients without PROM was 28.73 ±8. 8.72nm/l with p = 0.00. There was a significant relationship between vitamin D and PROM levels.
Conclusion: Based on the results of data analysis, it was found that there was a significant relationship between vitamin D levels and premature rupture of the amniotic sac. To examine more closely the relationship between maternal vitamin D levels and the occurrence of premature rupture of embryonic membranes, further research with a larger sample size and complete control of interfering factors is recommended.
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Type of Study: Research | Subject: زنان
Received: 2020/09/18 | Accepted: 2020/10/20 | Published: 2020/12/16

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