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University of Tehran
Abstract:   (99 Views)
Background: The aim of this study was to compare the effect of aerobic and resistance training on changes in ABCG4 gene expression and ApoA and ApoB variations in patients with coronary artery bypass surgery (CABG). Materials and Methods: 45 CABG-patients were divided into three groups: control (n = 12), aerobic exercise (n = 15) and resistance training. The aerobic and resistance training program was performed for eight-weeks with a frequency of three-sessions per week. Anthropometric variables, expression of ABCG4 gene and serum levels of Apo-A and Apo-B were measured before and after the training period. Data were analyzed using repeated measures of ANOVA and the significance level was considered 0.05. Results: Aerobic and resistance training significantly increased the expression of ABCG4 gene compared to the control group (p = 0.001), but there was no significant difference between the two training groups (p = 0.021). Significant differences were observed in serum levels of Apo-A and Apo-B in both aerobic and resistance training groups compared to the control group (p = 0.001). However, the difference between aerobic and resistance training groups was significant for Apo-A (p = 0.001), but not significant for Apo-B (p = 1.000). Also, the ratio of Apo-A to Apo-B was significantly different for the resistance training group compared to the control group (p = 0.001), but was not significant for the aerobic training group (p = 1.000). Conclusion: Resistance training improves cholesterol reverse transport regulators more than aerobic training and resistance training is recommended to regulate reverse cholesterol transfer.
     
Type of Study: Research | Subject: قلب و عروق
Received: 2021/03/13 | Accepted: 2021/07/3

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