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Lorestan University
Abstract:   (71 Views)
Introduction: High-intensity functional training is well performed by the elderly, but the effect of this type of training on factors related to brain health has not been studied. Therefore, the aim of this study was to investigate the effect of 8 weeks of high-intensity functional training on serum levels of BDNF, IGF-1 and VEGF in elderly men and women in Khorramabad.
Materials and Methods: In this quasi-experimental study, 23 subjects (7 males and 16 females) were divided into experimental group (n = 16) and control group (n = 7). The experimental group performed a high-intensity functional training protocol consisting of six exercises three sessions per week for eight weeks. Blood samples were taken from subjects 24 hours before and 48 hours after the training protocol in fasting state. Serum levels of BDNF, VEGF, IGF-1, LDL and HDL were measured. To analyze the data, Paired samples t-test and ANCOVA were used and the level of significance was considered as p<0.05.
Results: The results showed that in the experimental group, serum levels of BDNF (p = 0.0005), VEGF (p = 0.0005), IGF-1 (p = 0.001), LDL (p = 0.004) and HDL (p = 0.004) changed significantly but in the control group, serum levels of BDNF (p = 0.149), IGF-1 (p = 0.486), LDL (p = 0.897) and HDL (0.534) = p) nonsignificantly and VEGF (p = 0.010) significantly changed. Also, the results of ANCOVA showed a significant difference between the two groups in all variables (p <0.05).
Conclusion: Eight weeks of selected high-intensity functional training in elderly men and women increases serum levels of brain health-related factors. Therefore, high-intensity functional training is recommended to improve brain function in older men and women.
Type of Study: Research | Subject: فیزیولوژی انسانی
Received: 2021/04/25 | Accepted: 2021/09/11

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