Volume 25, Issue 4 (2-2024)                   yafte 2024, 25(4): 50-64 | Back to browse issues page

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Halalkhor F, Pourrahim Korkchi A, Siahkouhian M. Effect of saffron supplementation and endurance training on the concentration of interleukin-8, C-reactive protein, and clinical symptoms in outpatients with COVID-19. yafte 2024; 25 (4) :50-64
URL: http://yafte.lums.ac.ir/article-1-3699-en.html
Department of Sports Physiology, Faculty of Psychology and Educational Sciences, Mohaghegh Ardabili University, Ardabil, Iran
Abstract:   (362 Views)
Background: Covid-19 is considered a new disease across the globe. Physical activity reduces risk factors, and with anti-inflammatory and antioxidant properties, saffron is used as a traditional herbal medicine to treat cough and asthma. Therefore, the present study aimed to assess the effect of saffron supplementation and endurance training on the concentration of C-reactive protein, interleukin-8, and clinical symptoms in outpatients with COVID-19.
Materials and Methods: The present research was conducted based on a randomized, double-blind, four-group, pretest-posttest design. The statistical population of this research entailed all outpatients with COVID-19 referred to the health center of Keshkosrai. Among this population, 36 cases were randomly selected. The research hypotheses were evaluated using SPSS software at a significance level of P<0.05 using the statistical test of analysis of covariance (ANCOVA) and paired T-test.
Results: The results of ANCOVA demonstrated that after adjusting the effect of baseline values, height, and body mass index, there was a statistically significant difference between the groups in terms of the mean change of interleukin-8, C-reactive protein, partial oxygen pressure (SpO2), and body temperature (P<0.05). That is, the type of intervention can markedly affect the change of interleukin-8, C-reactive protein, partial oxygen pressure, and body temperature.
Conclusion: As evidenced by the obtained results, it is possible to use saffron as an auxiliary therapeutic method, as well as regular sports activity, which helps to control pathogens, including COVID-19, by boosting the body's immunity.

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Type of Study: Research | Subject: ایمونولوژی
Received: 2024/01/2 | Accepted: 2024/03/3 | Published: 2024/02/29

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