Volume 26, Issue 2 (6-2024)
yafte 2024, 26(2): 10-24 |
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Ghanbariani Gandom Bani A, Fathi M, Mirnasouri R, Goodarzi E. Effect of Curcumin Supplementation and Resistance Training on Oxidative Stress and Inflammatory Markers in Obese Men. yafte 2024; 26 (2) :10-24
URL: http://yafte.lums.ac.ir/article-1-3713-en.html
URL: http://yafte.lums.ac.ir/article-1-3713-en.html
Department of Sports Sciences, Faculty of Literature and Human Sciences, Lorestan University, Lorestan, Iran & Department of Sports Sciences, Faculty of Literature and Human Sciences, Lorestan University, Lorestan, Iran
Abstract: (562 Views)
Background: Physical activity with anti-inflammatory and antioxidant effects can play a critical role in the health of individuals. Therefore, the present study aimed to assess the impact of resistance training and curcumin consumption on inflammatory indicators and oxidative stress in obese men.
Materials and Methods: The present study was conducted based on a quasi-experimental design. The studied population consists of obese men aged 38-43 years. The sample size was estimated to be 40 individuals, who were randomly assigned to four groups of 10 using a random number table. The training program lasted for eight weeks, with three sessions per week. An 80 mg curcumin supplement was administered. Blood samples were collected before and after the final session. Data analysis involved one-way analysis of variance, paired t-test, and Tukey's post hoc test at a significance level of 0.05.
Results: The amount of catalase enzyme in resistance training groups (P=0.012), curcumin supplement (P=0.032), and resistance training group with curcumin consumption (P<0.001) were associated with a significant increase. Nonetheless, it was not significant in the control group (P=0.991). Furthermore, the levels of malondialdehyde, interleukin-6, C-reactive protein, and tumor necrosis factor-alpha in the experimental groups displayed a significant decrease (P<0.05), whereas these changes were not significant in the control group (P<0.05).
Conclusion: As evidenced by the obtained results, it can be stated that the consumption of curcumin may be effective in suppressing the inflammation caused by obesity. This is due to its potent antioxidant effects and its combination with resistance training.
Materials and Methods: The present study was conducted based on a quasi-experimental design. The studied population consists of obese men aged 38-43 years. The sample size was estimated to be 40 individuals, who were randomly assigned to four groups of 10 using a random number table. The training program lasted for eight weeks, with three sessions per week. An 80 mg curcumin supplement was administered. Blood samples were collected before and after the final session. Data analysis involved one-way analysis of variance, paired t-test, and Tukey's post hoc test at a significance level of 0.05.
Results: The amount of catalase enzyme in resistance training groups (P=0.012), curcumin supplement (P=0.032), and resistance training group with curcumin consumption (P<0.001) were associated with a significant increase. Nonetheless, it was not significant in the control group (P=0.991). Furthermore, the levels of malondialdehyde, interleukin-6, C-reactive protein, and tumor necrosis factor-alpha in the experimental groups displayed a significant decrease (P<0.05), whereas these changes were not significant in the control group (P<0.05).
Conclusion: As evidenced by the obtained results, it can be stated that the consumption of curcumin may be effective in suppressing the inflammation caused by obesity. This is due to its potent antioxidant effects and its combination with resistance training.
Type of Study: Research |
Subject:
فارماکولوژی
Received: 2024/03/1 | Accepted: 2024/05/18 | Published: 2024/08/24
Received: 2024/03/1 | Accepted: 2024/05/18 | Published: 2024/08/24
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